Bromo-PEG1-azide

Product Name: Bromo-PEG1-azide
CAS No.: 1144106-65-9
Chemical Name: Bromo-PEG1-azide
Synonyms: Bromo-PEG1-azide;Bromo-PEG1-C2-azide;Bromo-PEG1-azide, Bromo-PEG1-N3;1-azido-2-(2-bromoethoxy)ethane;1-Azido-2-(2-bromoethoxy)ethane/Bromo-PEG1-C2-azide;inhibit,PROTAC Linkers,Bromo-PEG-1-C2-azide,BromoPEG1C2azide,Inhibitor,Bromo PEG1 C2 azide
CBNumber: CB64849564
Molecular Formula: C4H8BrN3O
Formula Weight: 194.03
MOL File: 1144106-65-9.mol

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Bromo-PEG1-azide Property

storage temp.: Storage temp. 2-8°C
solubility: Soluble in DMSO, DCM, DMF
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24132
Product name: Bromo-PEG1-azide
Purity: 98%
Packaging: 1g
Price: $650
Updated: 2021/12/16

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Bromo-PEG1-azide Chemical Properties,Usage,Production

Description

Bromo-PEG1-azide is a bifunctional PEG linker with a bromide (Br)group and an azide(N3) group. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The bromide (Br) is a good leaving group for nucleophilic substitution reactions.

Uses

Bromo-PEG1-C2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG1-C2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Bromo-PEG1-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Bromo-PEG1-azide Suppliers

China 28 United States 3 Global 31

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View Lastest Price from Bromo-PEG1-azide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG1-Br 1144106-65-9
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

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Bromo-PEG1-azide

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1-Azido-2-(2-bromoethoxy)ethane/Bromo-PEG1-C2-azide

1-azido-2-(2-bromoethoxy)ethane

inhibit,PROTAC Linkers,Bromo-PEG-1-C2-azide,BromoPEG1C2azide,Inhibitor,Bromo PEG1 C2 azide

1144106-65-9

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