Azido-PEG1-acid
- Product Name
- Azido-PEG1-acid
- CAS No.
- 1393330-34-1
- Chemical Name
- Azido-PEG1-acid
- Synonyms
- Azido-PEG1-acid;CAS_1393330-34-1;N3-PEG1-CH2CH2COOH;Azido-PEG1-C2-acid;Azido-PEG1-acid, N3-PEG1-COOH;3-(2-Azidoethoxy)-propanoic acid;Propanoic acid, 3-(2-azidoethoxy)-
- CBNumber
- CB93062338
- Molecular Formula
- C5H9N3O3
- Formula Weight
- 159.15
- MOL File
- 1393330-34-1.mol
Azido-PEG1-acid Property
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Colourless
N-Bromosuccinimide Price
- Product number
- A965723
- Product name
- Azido-PEG1-acid
- Packaging
- 50mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- A965723
- Product name
- Azido-PEG1-acid
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- BP-20902
- Product name
- Azido-PEG1-acid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- AS106573
- Product name
- 3-(2-Azidoethoxy)-propanoicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- POL0002350
- Product name
- AZIDO-PEG1-ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.97
- Updated
- 2021/12/16
Azido-PEG1-acid Chemical Properties,Usage,Production
Description
Azido-PEG1-acid is a click chemistry reagent containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG1-acid Suppliers
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- 025-86918202 4000255188
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- 86-025-86918232
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- China
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- 0431-0431-80514535 19917294565
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- China
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- 027-65563561
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- 86-27-59218822
- sales@borenpharm.com
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- China
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- 0371-0371-55629727 13323845623
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- 037155629727
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- China
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- 0512-56316828
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- 0512-56316826
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- China
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- +86-156-80926068 +86-15680926068
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- China
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- 0371-55051623 18137891487
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- QQ：2853979817
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- China
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- 021-000000 13917643586;
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- China
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- Tel
- 0411-39042497
- Fax
- 0411-39042693
- sales@alphabiopharm.com
- Country
- China
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- 1951
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- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
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View Lastest Price from Azido-PEG1-acid manufacturers
- Product
- azido-PEG1-Acid 1393330-34-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23