Azido-PEG1-acid
- Product Name
- Azido-PEG1-acid
- CAS No.
- 1393330-34-1
- Chemical Name
- Azido-PEG1-acid
- Synonyms
- N3-PEG1-PA;Azido-PEG1-acid;CAS_1393330-34-1;N3-PEG1-CH2CH2COOH;Azido-PEG1-C2-acid;Azido-PEG1-acid, N3-PEG1-COOH;3-(2-Azidoethoxy)-propanoic acid;Propanoic acid, 3-(2-azidoethoxy)-
- CBNumber
- CB93062338
- Molecular Formula
- C5H9N3O3
- Formula Weight
- 159.15
- MOL File
- 1393330-34-1.mol
Azido-PEG1-acid Property
- storage temp.
- Refrigerator, under inert atmosphere
- solubility
- Chloroform (Slightly), Methanol (Slightly)
- form
- Oil
- color
- Colourless
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H226Flammable liquid and vapour
H241Heating may cause a fire or explosion
H301Toxic if swalloed
H372Causes damage to organs through prolonged or repeated exposure
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P220Keep/Store away from clothing/…/combustible materials.
P233Keep container tightly closed.
P234Keep only in original container.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P310Immediately call a POISON CENTER or doctor/physician.
P330Rinse mouth.
P370+P378In case of fire: Use … for extinction.
P370+P380+P375in case of fire: Evacuate area. Fight fire remotely due to the risk of explosion.
P403+P235Store in a well-ventilated place. Keep cool.
P405Store locked up.
P411Store at temperatures not exceeding … oC/…oF.
P420Store away from other materials.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- A965723
- Product name
- Azido-PEG1-acid
- Packaging
- 50mg
- Price
- $190
- Updated
- 2021/12/16
- Product number
- A965723
- Product name
- Azido-PEG1-acid
- Packaging
- 10mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- BP-20902
- Product name
- Azido-PEG1-acid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- AS106573
- Product name
- 3-(2-Azidoethoxy)-propanoicacid
- Purity
- 97%
- Packaging
- 250mg
- Price
- $240
- Updated
- 2021/12/16
- Product number
- POL0002350
- Product name
- AZIDO-PEG1-ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $504.97
- Updated
- 2021/12/16
Azido-PEG1-acid Chemical Properties,Usage,Production
Description
Azido-PEG1-acid is a click chemistry reagent containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Azido-PEG1-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Azido-PEG1-acid Suppliers
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
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- 55
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39999
- Advantage
- 60
- Tel
- 0431-80534353 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 3840
- Advantage
- 55
- Tel
- 027-65563561
- Fax
- 86-27-59218822
- sales@borenpharm.com
- Country
- China
- ProdList
- 1245
- Advantage
- 55
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 89689
- Advantage
- 60
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10026
- Advantage
- 58
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28769
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- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- 0371-55051623 18137891487
- Fax
- QQ：2853979817
- 3983243027@qq.com
- Country
- China
- ProdList
- 9815
- Advantage
- 58
- Tel
- 021-000000
- admin@jingshipharmatech.com
- Country
- China
- ProdList
- 9822
- Advantage
- 58
View Lastest Price from Azido-PEG1-acid manufacturers
- Product
- N3-PEG1-PA 1393330-34-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-04
- Product
- azido-PEG1-Acid 1393330-34-1
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23