ChemicalBook > CAS DataBase List > Azido-PEG1-acid

Azido-PEG1-acid

Product Name: Azido-PEG1-acid
CAS No.: 1393330-34-1
Chemical Name: Azido-PEG1-acid
Synonyms: Azido-PEG1-acid;CAS_1393330-34-1;N3-PEG1-CH2CH2COOH;Azido-PEG1-C2-acid;Azido-PEG1-acid, N3-PEG1-COOH;3-(2-Azidoethoxy)-propanoic acid;Propanoic acid, 3-(2-azidoethoxy)-
CBNumber: CB93062338
Molecular Formula: C5H9N3O3
Formula Weight: 159.15
MOL File: 1393330-34-1.mol

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Azido-PEG1-acid Property

storage temp.: Refrigerator, under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Oil
color: Colourless

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A965723
Product name: Azido-PEG1-acid
Packaging: 50mg
Price: $190
Updated: 2021/12/16

TRC

Product number: A965723
Product name: Azido-PEG1-acid
Packaging: 10mg
Price: $60
Updated: 2021/12/16

BroadPharm

Product number: BP-20902
Product name: Azido-PEG1-acid
Purity: 97%
Packaging: 250mg
Price: $240
Updated: 2021/12/16

Activate Scientific

Product number: AS106573
Product name: 3-(2-Azidoethoxy)-propanoicacid
Purity: 97%
Packaging: 250mg
Price: $240
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: POL0002350
Product name: AZIDO-PEG1-ACID
Purity: 95.00%
Packaging: 5MG
Price: $504.97
Updated: 2021/12/16

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Azido-PEG1-acid Chemical Properties,Usage,Production

Description

Azido-PEG1-acid is a click chemistry reagent containing an azide group with a terminal carboxylic acid. The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Azido-PEG1-C2-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG1-C2-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG1-acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Azido-PEG1-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: azido-PEG1-Acid 1393330-34-1
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1393330-34-1, Azido-PEG1-acidRelated Search:

Azido-PEG3-NHS ester Azido-PEG4-NHS Ester Ethyl acetate Hydrazoic acid Polyethylene Glycol Azido-PEG1-hydrazide Ethanol, 2-azido-, 4-methylbenzenesulfonate (ester) Bromo-PEG1-azide Azido-PEG1-t-butyl ester 2-Azidoethanol Carbamic acid, N-[2-(2-azidoethoxy)ethyl]-, 1,1-dimethylethyl ester Azido-PEG1-Val-Cit-PAB-OH Azido-PEG1-NHS ester N3-PEG7-OH Azido-PEG12-acid N3-PEG12-CH2CH2COOH Azido-PEG1-PFP ester N3-PEG6-CH2COOH

Propanoic acid, 3-(2-azidoethoxy)-

CAS_1393330-34-1

Azido-PEG1-acid

Azido-PEG1-C2-acid

Azido-PEG1-acid, N3-PEG1-COOH

3-(2-Azidoethoxy)-propanoic acid

N3-PEG1-CH2CH2COOH

1393330-34-1