Bromo-PEG8-t-butyl ester
- Product Name
- Bromo-PEG8-t-butyl ester
- CAS No.
- 1623792-00-6
- Chemical Name
- Bromo-PEG8-t-butyl ester
- Synonyms
- Br-PEG8-COOtBu;Bromo-PEG8-Boc;CAS_1623792-00-6;Br-PEG8-CH2CH2COOtBu;Br-PEG8-t-butyl ester;Bromo-PEG9-t-butyl ester;Bromo-PEG8-t-butyl ester;tert-Butyl 1-bromo-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate;4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-bromo-, 1,1-dimethylethyl ester;Br-PEG8-CH2CH2COOtBu/4,7,10,13,16,19,22,25-Octaoxaheptacosanoic acid, 27-bromo-, 1,1-dimethylethyl ester
- CBNumber
- CB43062454
- Molecular Formula
- C23H45BrO10
- Formula Weight
- 561.5
- MOL File
- 1623792-00-6.mol
Bromo-PEG8-t-butyl ester Property
- Boiling point:
- 557.0±45.0 °C(Predicted)
- Density
- 1.180±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-21975
- Product name
- Bromo-PEG8-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- BIPG1353
- Product name
- Bromo-PEG8-t-butyl ester
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
- Product number
- BP-21975
- Product name
- Bromo-PEG8-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $645
- Updated
- 2021/12/16
- Product number
- AS104144
- Product name
- Br-PEG8-CH2CH2COOtBu
- Purity
- 95+%
- Packaging
- 1g
- Price
- $673
- Updated
- 2021/12/16
- Product number
- BP-21975
- Product name
- Bromo-PEG8-t-butylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
Bromo-PEG8-t-butyl ester Chemical Properties,Usage,Production
Description
Bromo-PEG8-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Bromo-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG8-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Bromo-PEG8-t-butyl ester manufacturers
- Product
- Br-PEG8-COOtBu 1623792-00-6
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-25
- Product
- Bromo-PEG8-t-butyl ester 1623792-00-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21