Bromo-PEG5-Azide
- Product Name
- Bromo-PEG5-Azide
- CAS No.
- 1402411-90-8
- Chemical Name
- Bromo-PEG5-Azide
- Synonyms
- Br-PEG5-N3;Azido-PEG5-Br;N3-PEG5-CH2CH2Br;Bromo-PEG5-Azide;1-Azido-17-bromo-3,6,9,12,15-pentaoxaheptadecane;N3-PEG5-CH2CH2Br/3,6,9,12,15-Pentaoxaheptadecane, 1-azido-17-bromo-
- CBNumber
- CB13062448
- Molecular Formula
- C12H24BrN3O5
- Formula Weight
- 370.24
- MOL File
- 1402411-90-8.mol
Bromo-PEG5-Azide Property
- storage temp.
- -20°C, protect from light, stored under nitrogen
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- B750710
- Product name
- Bromo-PEG5-azide
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- B750710
- Product name
- Bromo-PEG5-azide
- Packaging
- 50mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- BP-21801
- Product name
- Bromo-PEG5-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-21801
- Product name
- Bromo-PEG5-azide
- Purity
- 98%
- Packaging
- 500MG
- Price
- $650
- Updated
- 2021/12/16
- Product number
- BIPG1332
- Product name
- Bromo-PEG5-Azide
- Packaging
- 250mg
- Price
- $740
- Updated
- 2021/12/16
Bromo-PEG5-Azide Chemical Properties,Usage,Production
Description
Bromo-PEG5-azide contain a bromide group and a terminal azide. The bromide (Br) is a very good leaving group for nucleophilic reactions. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. PEG5 spacer increases solubility in aqueous media.
Uses
Bromo-PEG6-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bromo-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromo-PEG5-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Bromo-PEG5-Azide Suppliers
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View Lastest Price from Bromo-PEG5-Azide manufacturers
- Product
- Azido-PEG5-Br 1402411-90-8
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23
- Product
- Bromo-PEG5-Azide 1402411-90-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 97%-99.9%
- Supply Ability
- 100kg
- Release date
- 2019-12-21