Bromoacetamido-PEG3-t-Butyl Ester
- Product Name
- Bromoacetamido-PEG3-t-Butyl Ester
- CAS No.
- 1807537-33-2
- Chemical Name
- Bromoacetamido-PEG3-t-Butyl Ester
- Synonyms
- BrCH2CONH-PEG3-COOtBu;Bromoacetamido-PEG3-C2-Boc;Bromoacetamido-PEG3-t-Butyl Ester;tert-butyl 1-bromo-2-oxo-6,9,13-trioxa-3-azahexadecan-16-oate;tert-Butyl 1-bromo-2-oxo-6,9,12-trioxa-3-azapentadecan-15-oate;4,7,10-Trioxa-13-azapentadecanoic acid, 15-bromo-14-oxo-, 1,1-dimethylethyl ester
- CBNumber
- CB53062431
- Molecular Formula
- C15H28BrNO6
- Formula Weight
- 398.29
- MOL File
- 1807537-33-2.mol
Bromoacetamido-PEG3-t-Butyl Ester Property
- Boiling point:
- 507.6±50.0 °C(Predicted)
- Density
- 1.252±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- pka
- 13.20±0.46(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
N-Bromosuccinimide Price
- Product number
- BP-22734
- Product name
- Bromoacetamido-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- BIPG1319
- Product name
- Bromoacetamido-PEG3-t-Butyl Ester
- Packaging
- 100mg
- Price
- $546
- Updated
- 2021/12/16
Bromoacetamido-PEG3-t-Butyl Ester Chemical Properties,Usage,Production
Description
Bromoacetamido-PEG3-t-butyl ester is a PEG linker containing a bromide group and a t-butyl protected carboxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
Uses
Bromoacetamido-PEG3-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Bromoacetamido-PEG3-t-Butyl Ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Bromoacetamido-PEG3-t-Butyl Ester manufacturers
- Product
- BrCH2CONH-PEG3-COOtBu 1807537-33-2
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-25