Benzyl-PEG5-Azide
- Product Name
- Benzyl-PEG5-Azide
- CAS No.
- 86770-72-1
- Chemical Name
- Benzyl-PEG5-Azide
- Synonyms
- CAS_86770-72-1;Benzyl-PEG5-N3;Benzyl-PEG4-N3;Benzyl-PEG4-azide;Benzyl-PEG5-Azide;BrCH2CONH-PEG2-N3;Bromoacetamido-PEG2-Azide;17-azido-1-phenyl-2,5,8,11,14-pentaoxaheptadecane;2,5,8,11,14-Pentaoxahexadecane, 16-azido-1-phenyl-;2-[2-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]ethoxy]ethoxymethylbenzene
- CBNumber
- CB73048688
- Molecular Formula
- C17H27N3O5
- Formula Weight
- 353.41338
- MOL File
- 86770-72-1.mol
Benzyl-PEG5-Azide Property
- solubility
- Soluble in Water, DMSO, DCM, DMF
N-Bromosuccinimide Price
- Product number
- BP-22868
- Product name
- Bromoacetamido-PEG2-azide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $560
- Updated
- 2021/12/16
- Product number
- BP-22868
- Product name
- Bromoacetamido-PEG2-azide
- Purity
- 98%
- Packaging
- 500mg
- Price
- $870
- Updated
- 2021/12/16
Benzyl-PEG5-Azide Chemical Properties,Usage,Production
Description
Bromoacetamido-PEG2-azide is a heterobifunctional PEG linker containing a reactive bromoacetamido and a terminal azide.The bromoacetamidogroup is a very reactive group for nucleophilic substitution. The azide group can react with alkyne, BCN, DBCO via Click Chemistry.
Uses
Benzyl-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Benzyl-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Benzyl-PEG5-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
Benzyl-PEG5-Azide Suppliers
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View Lastest Price from Benzyl-PEG5-Azide manufacturers
- Product
- Benzyl-PEG5-N3 86770-72-1
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-25