Propargyl-PEG3-Bromide
- Product Name
- Propargyl-PEG3-Bromide
- CAS No.
- 203740-63-0
- Chemical Name
- Propargyl-PEG3-Bromide
- Synonyms
- Alkyne-PEG3-Br;PROPARGYL-PEG3-BR;Propargyl-PEG3-Bromide;3-(2-(2-(2-bromoethoxy)ethoxy)ethoxy)prop-1-yne;1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-;3- (2- (2- (2-bromoethoxy) ethoxy) ethoxy) propa-1-yne;Propargyl-PEG3-Br/1-Propyne, 3-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]-
- CBNumber
- CB73062622
- Molecular Formula
- C9H15BrO3
- Formula Weight
- 251.12
- MOL File
- 203740-63-0.mol
Propargyl-PEG3-Bromide Property
- Boiling point:
- 287.8±25.0 °C(Predicted)
- Density
- 1.300±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, stored under nitrogen, away from moisture
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Liquid
- color
- Colorless to light yellow
Safety
- HS Code
- 2942000090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-22738
- Product name
- Propargyl-PEG3-bromide
- Purity
- 98%
- Packaging
- 250mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- BP-22738
- Product name
- Propargyl-PEG3-bromide
- Purity
- 98%
- Packaging
- 1g
- Price
- $890
- Updated
- 2021/12/16
- Product number
- B-1405
- Product name
- Propargyl-PEG3-Br
- Purity
- 97%
- Packaging
- 1g
- Price
- $412.5
- Updated
- 2021/12/16
Propargyl-PEG3-Bromide Chemical Properties,Usage,Production
Description
Propargyl-PEG3-bromide comprises a propargyl group and a bromide group. The propargyl group reacts with azide-bearing compounds or biomolecules in Click Chemistry to yield a stable triazole linkage; copper will be needed as a catalyst.
Uses
Propargyl-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-bromide is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG3-Bromide Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG3-Bromide Suppliers
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- 400-400-164-7117 18317119277
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- United States
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View Lastest Price from Propargyl-PEG3-Bromide manufacturers
- Product
- Propargyl-PEG3-Br 203740-63-0
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG3-bromide 203740-63-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26