Propargyl-PEG7-acid
- Product Name
- Propargyl-PEG7-acid
- CAS No.
- 2093154-00-6
- Chemical Name
- Propargyl-PEG7-acid
- Synonyms
- CAS_2093154-00-6;Propargyl-PEG7-acid;Propargyl-PEG6-C2-COOH;Propargyl-PEG6-CH2CH2COOH;4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid;Propargyl-PEG6-CH2CH2COOH/4,7,10,13,16,19,22-Heptaoxapentacos-24-ynoic acid
- CBNumber
- CB53134213
- Molecular Formula
- C18H32O9
- Formula Weight
- 392.44
- MOL File
- 2093154-00-6.mol
Propargyl-PEG7-acid Property
- storage temp.
- 2-8°C, stored under nitrogen
- form
- Liquid
- color
- Light yellow to yellow
N-Bromosuccinimide Price
- Product number
- BP-23423
- Product name
- Propargyl-PEG7-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $430
- Updated
- 2021/12/16
- Product number
- AS104185
- Product name
- Propargyl-PEG6-CH2CH2COOH
- Purity
- 95+%
- Packaging
- 1g
- Price
- $588
- Updated
- 2021/12/16
- Product number
- BIPG1708
- Product name
- Propargyl-PEG7-acid
- Packaging
- 250mg
- Price
- $681
- Updated
- 2021/12/16
- Product number
- B-1137
- Product name
- Propargyl-PEG6-CH2CH2COOH
- Purity
- 97%
- Packaging
- 1g
- Price
- $495
- Updated
- 2021/12/16
Propargyl-PEG7-acid Chemical Properties,Usage,Production
Description
Propargyl-PEG7-acid is a reagent with a propargyl group with a carboxylic acid. The carboxylic acid reacts with primary amines under the activation of EDC or HATU. The propargyl group can participate in azide-alkyne Click Chemistry reaction to form triazole linkage, copper is required as a catalyst. The PEG spacer increases the hydrophilicity of the molecule.
Uses
Propargyl-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG7-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG7-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Cleavable Linker; PEGs
References
[1] Anandan Palani, et al. Insulin-incretin conjugates. WO2017160669A1.
Propargyl-PEG7-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG7-acid Suppliers
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View Lastest Price from Propargyl-PEG7-acid manufacturers
- Product
- Propargyl-PEG6-CH2CH2COOH 2093154-00-6
- Price
- US $557.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300KG
- Release date
- 2025-11-19
- Product
- Propargyl-PEG7-acid 2093154-00-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26