Propargyl-PEG9-amine
- Product Name
- Propargyl-PEG9-amine
- CAS No.
- 2093153-98-9
- Chemical Name
- Propargyl-PEG9-amine
- Synonyms
- NH2-PEG9-Propargyl;Propargyl-PEG9-NH2;Propargyl-PEG9-amine;3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-amine;Propargyl-PEG9-NH2/3,6,9,12,15,18,21,24,27-Nonaoxatriacont-29-yn-1-amine
- CBNumber
- CB93373764
- Molecular Formula
- C21H41NO9
- Formula Weight
- 451.55
- MOL File
- 2093153-98-9.mol
Propargyl-PEG9-amine Property
- Boiling point:
- 512.3±45.0 °C(Predicted)
- Density
- 1.075±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 8.74±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- BP-23419
- Product name
- Propargyl-PEG9-amine
- Purity
- 95%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- AS104194
- Product name
- Propargyl-PEG9-NH2
- Purity
- 95+%
- Packaging
- 1g
- Price
- $721
- Updated
- 2021/12/16
- Product number
- B-1147
- Product name
- Propargyl-PEG9-NH2
- Purity
- 97%
- Packaging
- 0.25g
- Price
- $265.84
- Updated
- 2021/12/16
Propargyl-PEG9-amine Chemical Properties,Usage,Production
Description
Propargyl-PEG9-amine has a propargyl group and an amine group. The amine group reacts with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) to form amide bonds. The propargyl group reacts with azides to form triazole linkage with the presence of copper as a catalyst.
Uses
Propargyl-PEG9-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG9-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Guangrong Zheng, et al. Bcl-2 proteins degraders for cancer treatment. WO2019144117A1.
Propargyl-PEG9-amine Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG9-amine Suppliers
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View Lastest Price from Propargyl-PEG9-amine manufacturers
- Product
- Propargyl-PEG9-NH2 2093153-98-9
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG9-amine 2093153-98-9
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26