Propargyl-PEG6-amine

Product Name: Propargyl-PEG6-amine
CAS No.: 1198080-04-4
Chemical Name: Propargyl-PEG6-amine
Synonyms: Alkyne-PEG6-NH2;NH2-PEG6-Propargyl;PROPARGYL-PEG6-NH2;Propyne-PEG6-amine;Propargyl-PEG6-amine;Propynyl Hexapolyethylene Glycol Amino;3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-amine;3,6,9,12,15,18-Hexaoxaheneicos-20-yn-1-amine;Propargyl-PEG6-NH2/3,6,9,12,15,18-Hexaoxaheneicos-20-yn-1-amine
CBNumber: CB83062634
Molecular Formula: C15H29NO6
Formula Weight: 319.39
MOL File: 1198080-04-4.mol

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Propargyl-PEG6-amine Property

Boiling point:: 401.8±40.0 °C(Predicted)
Density: 1.058±0.06 g/cm3(Predicted)
storage temp.: Storage temp. -20°C
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 8.74±0.10(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: P839443
Product name: Propargyl-PEG6-amine
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-22876
Product name: Propargyl-PEG6-amine
Purity: 98%
Packaging: 250mg
Price: $185
Updated: 2021/12/16

Activate Scientific

Product number: AS104192
Product name: Propargyl-PEG6-NH2
Purity: 95+%
Packaging: 1g
Price: $631
Updated: 2021/12/16

purepeg

Product number: 433006
Product name: HC≡C-CH2-PEG6-NH2
Purity: min.97%
Packaging: 250mg
Price: $250
Updated: 2021/12/16

Acrotein

Product number: B-1145
Product name: Propargyl-PEG6-NH2
Purity: 97%
Packaging: 1g
Price: $495
Updated: 2021/12/16

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Propargyl-PEG6-amine Chemical Properties,Usage,Production

Description

Propargyl-PEG6-amine is a crosslinker with a hydrophilic PEG spacer which can increase the hydrophilicity of the molecule in aqueous environment. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry.

Uses

Propargyl-PEG6-NH2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG6-NH2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG6-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG6-amine Suppliers

China 57 United States 5 Global 62

Alabiochem Tech.Co., Ltd.

Tel: 512-58900862 400-0707518
Fax: 0086-512-56765862
Email: sales@alabiochem.com
Country: China
ProdList: 970
Advantage: 59

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3935
Advantage: 55

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
Email: 2885676761@qq.com
Country: China
ProdList: 10110
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12306
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
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Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
Fax: -
Email: sales09@leobiochem.com
Country: China
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

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View Lastest Price from Propargyl-PEG6-amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG6-amine 1198080-04-4
Price: US $0.00/g
Min. Order: 5g
Purity: >98.00%
Supply Ability: 5g
Release date: 2024-03-26

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Propargyl-PEG6-amine

Propyne-PEG6-amine

Alkyne-PEG6-NH2

PROPARGYL-PEG6-NH2

3,6,9,12,15,18-Hexaoxaheneicos-20-yn-1-amine

Propargyl-PEG6-NH2/3,6,9,12,15,18-Hexaoxaheneicos-20-yn-1-amine

3,6,9,12,15,18-Hexaoxahenicos-20-yn-1-amine

Propynyl Hexapolyethylene Glycol Amino

NH2-PEG6-Propargyl

1198080-04-4

1197080-04-4

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