Propargyl-PEG8-CH2CH2COOH
- Product Name
- Propargyl-PEG8-CH2CH2COOH
- CAS No.
- 1613752-50-3
- Chemical Name
- Propargyl-PEG8-CH2CH2COOH
- Synonyms
- Propargyl-PEG8-C2-COOH;Propargyl-PEG8-CH2CH2COOH;4,7,10,13,16,19,22,25,28-Nonaoxahentriacont-30-ynoic acid;Propargyl-PEG8-CH2CH2COOH/4,7,10,13,16,19,22,25,28-Nonaoxahentriacont-30-ynoic acid
- CBNumber
- CB73975591
- Molecular Formula
- C22H40O11
- Formula Weight
- 480.55
- MOL File
- 1613752-50-3.mol
Propargyl-PEG8-CH2CH2COOH Property
- Boiling point:
- 563.1±50.0 °C(Predicted)
- Density
- 1.124±0.06 g/cm3(Predicted)
- storage temp.
- Store at Room Tem.
- pka
- 4.28±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B-1139
- Product name
- Propargyl-PEG8-CH2CH2COOH
- Purity
- 97%
- Packaging
- 0.5g
- Price
- $366.66
- Updated
- 2021/12/16
Propargyl-PEG8-CH2CH2COOH Chemical Properties,Usage,Production
Uses
Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG9-acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Biological Activity
Propargyl-PEG9-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Propargyl-PEG8-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG8-CH2CH2COOH Suppliers
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- 400-164-7117 13681763483
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- +86-21-61629029
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- China
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View Lastest Price from Propargyl-PEG8-CH2CH2COOH manufacturers
- Product
- Propargyl-PEG8-CH2CH2COOH 1613752-50-3
- Price
- US $891.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg
- Release date
- 2025-11-22
- Product
- Propargyl-PEG9-acid 1613752-50-3
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26