ChemicalBook > CAS DataBase List > Propargyl-PEG3-azide

Propargyl-PEG3-azide

Product Name
Propargyl-PEG3-azide
CAS No.
932741-18-9
Chemical Name
Propargyl-PEG3-azide
Synonyms
Alkyne-PEG3-NH2;HC≡C-CH2-PEG3-NH2;PROPARGYL-PEG3-NH2;Propargyl-PEG3-azide;Azido-PEG3-propargyl;3-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)prop-1-yne;1-Propyne, 3-[2-[2-(2-azidoethoxy)ethoxy]ethoxy]-
CBNumber
CB43062621
Molecular Formula
C9H15N3O3
Formula Weight
213.24
MOL File
932741-18-9.mol
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P839893
Product name
Propargyl-PEG3-Amine
Packaging
10mg
Price
$65
Updated
2021/12/16
Apolloscientific
Product number
BIPG1724
Product name
Propargyl-PEG3-amine
Packaging
100mg
Price
$449
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002521
Product name
PROPARGYL-PEG3-AZIDE
Purity
95.00%
Packaging
5MG
Price
$501.99
Updated
2021/12/16
Apolloscientific
Product number
BIPG1728
Product name
Propargyl-PEG3-azide
Packaging
250mg
Price
$546
Updated
2021/12/16
Chemenu
Product number
CM327857
Product name
2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanamine
Purity
95%+
Packaging
10g
Price
$937
Updated
2021/12/16
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Propargyl-PEG3-azide Chemical Properties,Usage,Production

Uses

Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Biological Activity

Propargyl-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

IC 50

PEGs

References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Propargyl-PEG3-azide Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG3-azide Suppliers

T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Tongling HengYou Biotechnology Co., Ltd.
Tel
021-50426030 13856289449
Fax
021-50426030
Email
2630597085@qq.com
Country
China
ProdList
1889
Advantage
55
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80534353 19917294565
Email
et@chemextension.com
Country
China
ProdList
3828
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10028
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
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View Lastest Price from Propargyl-PEG3-azide manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG3-N3 932741-18-9
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26
R&D Scientific Inc.
Product
Propargyl-PEG3-azide 932741-18-9
Price
US $1800.00/g
Min. Order
1g
Purity
95
Supply Ability
1 Kg
Release date
2024-02-12