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Propargyl-PEG3-t-butyl ester

Product Name
Propargyl-PEG3-t-butyl ester
CAS No.
1374658-84-0
Chemical Name
Propargyl-PEG3-t-butyl ester
Synonyms
Propargyl-PEG3-Boc;Propargyl-PEG3-COOtBu;Alkyne-PEG3-CH2CH2COOtBu;Propargyl-PEG2-C2-COOtBu;Propargyl-PEG3-t-Bu Ester;PROPARGYL-PEG3-CH2CH2COOTBU;Propargyl-PEG3-t-butyl ester;3-[2-[2-(2-Boc-ethoxy)ethoxy]ethoxy]-1-propyne;tert-butyl 3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoate;Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
CBNumber
CB53048730
Molecular Formula
C14H24O5
Formula Weight
272.34
MOL File
1374658-84-0.mol
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Propargyl-PEG3-t-butyl ester Property

Boiling point:
337.2±27.0 °C(Predicted)
Density 
1.023±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, stored under nitrogen
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
P839548
Product name
Propargyl-Peg3-T-ButylEster
Packaging
10mg
Price
$45
Updated
2021/12/16
TRC
Product number
P839548
Product name
Propargyl-Peg3-T-ButylEster
Packaging
100mg
Price
$310
Updated
2021/12/16
Activate Scientific
Product number
AS107934
Product name
Propargyl-PEG3-CH2CH2COOtBu
Purity
97%
Packaging
1g
Price
$464
Updated
2021/12/16
BroadPharm
Product number
BP-20677
Product name
Propargyl-PEG3-t-butylester
Purity
98%
Packaging
250mg
Price
$230
Updated
2021/12/16
Apolloscientific
Product number
BIPG1744
Product name
Propargyl-PEG3-t-butyl ester
Packaging
250mg
Price
$565
Updated
2021/12/16
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Propargyl-PEG3-t-butyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG3-t-butyl ester consists of an alkyne group and a t-butyl ester group. The alkyne groupreacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The protected carboxyl group can be deprotected under acidic conditions.

Uses

Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG3-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG3-t-butyl ester Suppliers

Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
39999
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5873
Advantage
58
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66028182 17714375163
Email
yftan@aikonchem.com
Country
China
ProdList
16676
Advantage
50
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80534353 19917294565
Email
et@chemextension.com
Country
China
ProdList
3827
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10028
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28772
Advantage
58
SHANGHAI FDC-CHEMICAL CO.,LTD
Tel
021-61469567 13482353728
Fax
021-61161605
Email
sales@fdc-chemical.com
Country
China
ProdList
9964
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ:2853979817
Email
3983243027@qq.com
Country
China
ProdList
9802
Advantage
58
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View Lastest Price from Propargyl-PEG3-t-butyl ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Propargyl-PEG3-COOtBu 1374658-84-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-03
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG3-COOtBu 1374658-84-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26
Career Henan Chemical Co
Product
Propargyl-PEG3-t-butyl ester 1374658-84-0
Price
US $1.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
500kg
Release date
2018-08-19

1374658-84-0, Propargyl-PEG3-t-butyl esterRelated Search:


  • Propargyl-PEG3-COOtBu
  • Alkyne-PEG3-CH2CH2COOtBu
  • PROPARGYL-PEG3-CH2CH2COOTBU
  • Propargyl-PEG3-t-butyl ester
  • Propargyl-PEG3-Boc
  • Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • Propargyl-PEG3-t-Bu Ester
  • Propargyl-PEG2-CH2CH2COOtBu/Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
  • Propargyl-PEG2-C2-COOtBu
  • tert-butyl 3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoate
  • 3-[2-[2-(2-Boc-ethoxy)ethoxy]ethoxy]-1-propyne
  • 1374658-84-0
  • peg