Propargyl-PEG3-t-butyl ester
- Product Name
- Propargyl-PEG3-t-butyl ester
- CAS No.
- 1374658-84-0
- Chemical Name
- Propargyl-PEG3-t-butyl ester
- Synonyms
- Propargyl-PEG3-Boc;Propargyl-PEG3-COOtBu;Alkyne-PEG3-CH2CH2COOtBu;Propargyl-PEG2-C2-COOtBu;Propargyl-PEG3-t-Bu Ester;PROPARGYL-PEG3-CH2CH2COOTBU;Propargyl-PEG3-t-butyl ester;3-[2-[2-(2-Boc-ethoxy)ethoxy]ethoxy]-1-propyne;tert-butyl 3-[2-(2-prop-2-ynoxyethoxy)ethoxy]propanoate;Propanoic acid, 3-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB53048730
- Molecular Formula
- C14H24O5
- Formula Weight
- 272.34
- MOL File
- 1374658-84-0.mol
Propargyl-PEG3-t-butyl ester Property
- Boiling point:
- 337.2±27.0 °C(Predicted)
- Density
- 1.023±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, stored under nitrogen
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P839548
- Product name
- Propargyl-Peg3-T-ButylEster
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P839548
- Product name
- Propargyl-Peg3-T-ButylEster
- Packaging
- 100mg
- Price
- $310
- Updated
- 2021/12/16
- Product number
- AS107934
- Product name
- Propargyl-PEG3-CH2CH2COOtBu
- Purity
- 97%
- Packaging
- 1g
- Price
- $464
- Updated
- 2021/12/16
- Product number
- BP-20677
- Product name
- Propargyl-PEG3-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $230
- Updated
- 2021/12/16
- Product number
- BIPG1744
- Product name
- Propargyl-PEG3-t-butyl ester
- Packaging
- 250mg
- Price
- $565
- Updated
- 2021/12/16
Propargyl-PEG3-t-butyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG3-t-butyl ester consists of an alkyne group and a t-butyl ester group. The alkyne groupreacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions. The protected carboxyl group can be deprotected under acidic conditions.
Uses
Propargyl-PEG3-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG3-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG3-t-butyl ester Suppliers
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View Lastest Price from Propargyl-PEG3-t-butyl ester manufacturers
- Product
- Propargyl-PEG3-COOtBu 1374658-84-0
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2026-02-03
- Product
- Propargyl-PEG3-COOtBu 1374658-84-0
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-26
- Product
- Propargyl-PEG3-t-butyl ester 1374658-84-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 95%
- Supply Ability
- 500kg
- Release date
- 2018-08-19