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Propargyl-PEG5-t-butyl ester

Product Name
Propargyl-PEG5-t-butyl ester
CAS No.
1245823-50-0
Chemical Name
Propargyl-PEG5-t-butyl ester
Synonyms
Propargyl-PEG5-COOtBu;PropargylPEG5-tBu ester;Propargyl-PEG4-C2-COOtBu;Alkyne-PEG5-CH2CH2COOtBu;Propargyl-PEG4-CH2CH2-Boc;PROPARGYL-PEG5-CH2CH2COOTBU;Propargyl-PEG5-t-butyl ester;1-Boc-3,6,9,12,15-pentaoxaoctadec-17-yne;tert-butyl 4,7,10,13,16-pentaoxanonadec-18-ynoate;4,7,10,13,16-Pentaoxanonadec-18-ynoic acid, 1,1-dimethylethyl ester
CBNumber
CB73048734
Molecular Formula
C18H32O7
Formula Weight
360.44
MOL File
1245823-50-0.mol
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Propargyl-PEG5-t-butyl ester Property

Boiling point:
420.6±40.0 °C(Predicted)
Density 
1.045±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

BroadPharm
Product number
bp-20651
Product name
Propargyl-PEG5-t-butyl ester
Purity
98%
Packaging
250MG
Price
$230
Updated
2026/05/24
BroadPharm
Product number
bp-20651
Product name
Propargyl-PEG5-t-butyl ester
Purity
98%
Packaging
500MG
Price
$450
Updated
2026/05/24
BroadPharm
Product number
bp-20651
Product name
Propargyl-PEG5-t-butyl ester
Purity
98%
Packaging
1G
Price
$690
Updated
2026/05/24
BroadPharm
Product number
bp-20651
Product name
Propargyl-PEG5-t-butyl ester
Purity
98%
Packaging
5G
Price
$1500
Updated
2026/05/24
Matrix Scientific
Product number
303094
Product name
tert-Butyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate
Packaging
250.00mg
Price
$38
Updated
2026/05/19
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Propargyl-PEG5-t-butyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG5-t-butyl ester has one of the functional groups protected by t-butyl group. The protection can be removed under acidic conditions. The propargyl group forms triazole linkages with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry. The PEG units help improving the water-solubility of the molecule in aqueous media.

Uses

Propargyl-PEG4-CH2CH2-Boc is a non-cleavable ADC linker that can be used to synthesize ADC inhibitors of Galectin-3. Propargyl-PEG4-CH2CH2-Boc is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-CH2CH2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Non-cleavable Linker; Alkyl/ether

References

[1] Zhang H, et al. Thiodigalactoside-Bovine Serum Albumin Conjugates as High-Potency Inhibitors of Galectin-3: An Outstanding Example of Multivalent Presentation of Small Molecule Inhibitors. Bioconjug Chem. 2018 Apr 18;29(4):1266-1275. DOI:10.1021/acs.bioconjchem.8b00047

Propargyl-PEG5-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG5-t-butyl ester Suppliers

Alabiochem Tech.Co., Ltd.
Tel
512-58900862 400-0707518
Fax
0086-512-56765862
Email
sales@alabiochem.com
Country
China
ProdList
988
Advantage
59
Chengdu Pukang Biotechnology Co., Ltd
Tel
028-82550498 18217049878
Fax
086-28-82550468
Email
cassie.gao@pu-kang.com
Country
China
ProdList
468
Advantage
58
Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770;
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5870
Advantage
58
Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
Tel
0431-80534353 19917294565
Email
et@chemextension.com
Country
China
ProdList
3855
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Zhengzhou Acme Chemical Co., Ltd.
Tel
0371-0371-55629727 13323845623
Fax
037155629727
Email
2885676761@qq.com
Country
China
ProdList
10021
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28769
Advantage
58
Jiaxing Deyi Chemical Co., Ltd.
Tel
86-0573-85866609 13325730825
Fax
0573-85866609
Email
945717149@qq.com
Country
China
ProdList
8997
Advantage
58
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View Lastest Price from Propargyl-PEG5-t-butyl ester manufacturers

XIAMEN SINOPEG BIOTECH CO., LTD.
Product
Propargyl-PEG5-COOtBu 1245823-50-0
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%
Supply Ability
1g/bottle, 10g/bottle, 100g/bottle
Release date
2026-02-03
Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG5-COOtBu 1245823-50-0
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

1245823-50-0, Propargyl-PEG5-t-butyl esterRelated Search:


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