Diethylene Glycol Bis(2-propynyl) Ether
- Product Name
- Diethylene Glycol Bis(2-propynyl) Ether
- CAS No.
- 126422-57-9
- Chemical Name
- Diethylene Glycol Bis(2-propynyl) Ether
- Synonyms
- Bis-propargyl-PEG3;Alkyne-PEG3-Alkyne;Bis-propargyl-PEG2;PROPARGYL-PEG3-PROPARGYL;4,7,10-Trioxa-1,12-tridecadiyne;4,7,10-trioxahexadeca-1,12-diyne;α,ω-bis(O-propargyl)diethylene glycol;Diethylene Glycol Bis(2-propynyl) Ether;Diethylene Glycol Bis(2-propynyl) Ether >3-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]-1-propyne
- CBNumber
- CB43038295
- Molecular Formula
- C10H14O3
- Formula Weight
- 182.22
- MOL File
- 126422-57-9.mol
Diethylene Glycol Bis(2-propynyl) Ether Property
- Boiling point:
- 103°C/6mmHg(lit.)
- Density
- 1.011±0.06 g/cm3(Predicted)
- refractive index
- 1.4610 to 1.4650
- storage temp.
- Storage temp. 2-8°C
- form
- clear liquid
- color
- Colorless to Light yellow
Safety
- HS Code
- 2909.19.6000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H227Combustible liquid
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D4581
- Product name
- Diethylene Glycol Bis(2-propynyl) Ether
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $163
- Updated
- 2025/07/31
- Product number
- D4581
- Product name
- Diethylene Glycol Bis(2-propynyl) Ether
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $564
- Updated
- 2025/07/31
- Product number
- B523145
- Product name
- bis-Propargyl-PEG3
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 5972AL
- Product name
- 3-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]-1-propyne
- Packaging
- 1g
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 39717
- Product name
- Diethyleneglycolbis(2-propynyl)ether,98%(GC)
- Purity
- 98%(GC)
- Packaging
- 5G
- Price
- $154.56
- Updated
- 2021/12/16
Diethylene Glycol Bis(2-propynyl) Ether Chemical Properties,Usage,Production
Description
Bis-propargyl-PEG3 is a crosslinker with alkyne groups at both ends of the molecule. The alkyne groups react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage.
Uses
Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2]. Bis-propargyl-PEG2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Shenoi RA, et al. Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators. Biomacromolecules. 2012 Oct 8;13(10):3018-30. DOI:10.1021/bm300959h
[2] Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.
Diethylene Glycol Bis(2-propynyl) Ether Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Diethylene Glycol Bis(2-propynyl) Ether manufacturers
- Product
- Bis-propargyl-PEG3 126422-57-9
- Price
- US $0.00/g
- Min. Order
- 25g
- Purity
- >98.00%
- Supply Ability
- 25g
- Release date
- 2024-03-26