ChemicalBook > CAS DataBase List > Diethylene Glycol Bis(2-propynyl) Ether

Diethylene Glycol Bis(2-propynyl) Ether

Product Name
Diethylene Glycol Bis(2-propynyl) Ether
CAS No.
126422-57-9
Chemical Name
Diethylene Glycol Bis(2-propynyl) Ether
Synonyms
Bis-propargyl-PEG3;Alkyne-PEG3-Alkyne;Bis-propargyl-PEG2;PROPARGYL-PEG3-PROPARGYL;4,7,10-Trioxa-1,12-tridecadiyne;4,7,10-trioxahexadeca-1,12-diyne;α,ω-bis(O-propargyl)diethylene glycol;Diethylene Glycol Bis(2-propynyl) Ether;Diethylene Glycol Bis(2-propynyl) Ether >3-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]-1-propyne
CBNumber
CB43038295
Molecular Formula
C10H14O3
Formula Weight
182.22
MOL File
126422-57-9.mol
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Diethylene Glycol Bis(2-propynyl) Ether Property

Boiling point:
103°C/6mmHg(lit.)
Density 
1.011±0.06 g/cm3(Predicted)
refractive index 
1.4610 to 1.4650
storage temp. 
Storage temp. 2-8°C
form 
clear liquid
color 
Colorless to Light yellow
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Safety

HS Code 
2909.19.6000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H227Combustible liquid

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
D4581
Product name
Diethylene Glycol Bis(2-propynyl) Ether
Purity
>98.0%(GC)
Packaging
5g
Price
$163
Updated
2025/07/31
TCI Chemical
Product number
D4581
Product name
Diethylene Glycol Bis(2-propynyl) Ether
Purity
>98.0%(GC)
Packaging
25g
Price
$564
Updated
2025/07/31
TRC
Product number
B523145
Product name
bis-Propargyl-PEG3
Packaging
50mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
5972AL
Product name
3-[2-[2-(2-Propynyloxy)ethoxy]ethoxy]-1-propyne
Packaging
1g
Price
$104
Updated
2021/12/16
Chem-Impex
Product number
39717
Product name
Diethyleneglycolbis(2-propynyl)ether,98%(GC)
Purity
98%(GC)
Packaging
5G
Price
$154.56
Updated
2021/12/16
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Diethylene Glycol Bis(2-propynyl) Ether Chemical Properties,Usage,Production

Description

Bis-propargyl-PEG3 is a crosslinker with alkyne groups at both ends of the molecule. The alkyne groups react with azide-bearing compounds or biomolecules via copper catalyzed Click Chemistry to form a stable triazole linkage.

Uses

Bis-propargyl-PEG2 is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-propargyl-PEG2 is used for the synthesis of demethylvancomycin dimers[1][2]. Bis-propargyl-PEG2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Shenoi RA, et al. Synthesis, characterization, and biocompatibility of biodegradable hyperbranched polyglycerols from acid-cleavable ketal group functionalized initiators. Biomacromolecules. 2012 Oct 8;13(10):3018-30. DOI:10.1021/bm300959h
[2] Jiang, et al. Design, synthesis and biological activity of novel demethylvancomycin dimers against vancomycin-resistant enterococcus faecalis. Tetrahedron, 2018: 74(27), 3527–3533.

Diethylene Glycol Bis(2-propynyl) Ether Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Diethylene Glycol Bis(2-propynyl) Ether manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Bis-propargyl-PEG3 126422-57-9
Price
US $0.00/g
Min. Order
25g
Purity
>98.00%
Supply Ability
25g
Release date
2024-03-26

126422-57-9, Diethylene Glycol Bis(2-propynyl) EtherRelated Search:

Propargyl-PEG5-t-butyl ester 2-[2-(PROP-2-YNYLOXY)ETHOXY]ETHAN-1-OL Propargyl-PEG3-t-butyl ester Propargyl-PEG4-NHS ester propargyl-PEG3-Acid Propargyl-PEG3-NHS ester Propargyl-PEG5-alcohol Bis-propargyl-PEG10 Bis-propargyl-PEG8 Bis-Propargyl-PEG7 Bis-propargyl-PEG11 DIPROPARGYL ETHER Bis-Propargyl-PEG10 Bis-Propargyl-PEG9 Bis-Propargyl-PEG4 alpha, oMega-Dipropionic acid triethylene glycol Bis-propargyl-PEG6 4,7,10,13,16-Pentaoxanonadeca-1,18-diyne

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  • Bis-propargyl-PEG2/3-(2-(2-(Prop-2-ynyloxy)ethoxy)ethoxy)prop-1-yne
  • 126422-57-9
  • peg