Bis-Propargyl-PEG4
- Product Name
- Bis-Propargyl-PEG4
- CAS No.
- 126422-58-0
- Chemical Name
- Bis-Propargyl-PEG4
- Synonyms
- Alkyne-PEG4-Alkyne;Bis-Propargyl-PEG4;PROPARGYL-PEG4-PROPARGYL;4,7,10,13-Tetraoxahexadeca-1,15-diyne;α,ω-bis(O-propargyl)triethylene glycol;Bis-propargyl-PEG3/4,7,10,13-Tetraoxahexadeca-1,15-diyne
- CBNumber
- CB73048709
- Molecular Formula
- C12H18O4
- Formula Weight
- 226.27
- MOL File
- 126422-58-0.mol
Bis-Propargyl-PEG4 Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B523970
- Product name
- Bis-propargyl-PEG4
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-21071
- Product name
- Bis-propargyl-PEG4
- Purity
- 98%
- Packaging
- 250mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- BP-21071
- Product name
- Bis-propargyl-PEG4
- Purity
- 98%
- Packaging
- 500mg
- Price
- $270
- Updated
- 2021/12/16
- Product number
- POL0002395
- Product name
- BIS PROPARGYL-PEG4
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $407.4
- Updated
- 2021/12/16
- Product number
- BIPG1299
- Product name
- Bis-Propargyl-PEG4
- Packaging
- 250mg
- Price
- $449
- Updated
- 2021/12/16
Bis-Propargyl-PEG4 Chemical Properties,Usage,Production
Description
Bis-propargyl-PEG4 enables Click Chemistry reactions with azide compounds via copper catalyzed azide-alkyne Click Chemistry. The PEG units enhance the solubility of the molecule in aqueous media.
Uses
Bis-propargyl-PEG3 is a PEG-based PROTAC linker used in the synthesis of PROTACs. Bis-propargyl-PEG3 is used in the synthesis of zinc-dipicolylamine (ZnDPA) complexes with antiplasmodial activity[1] [2]. Bis-propargyl-PEG3 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Pearlie BURNETTE, et al. Dimeric immuno-modulatory compounds against cereblon-based mechanisms. WO2020014489A2.
[2] Rice DR, et al. Antiplasmodial activity of targeted zinc(II)-dipicolylamine complexes. Bioorg Med Chem. 2017 May 15;25(10):2754-2760. DOI:10.1016/j.bmc.2017.03.050
Bis-Propargyl-PEG4 Preparation Products And Raw materials
Raw materials
Preparation Products
Bis-Propargyl-PEG4 Suppliers
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View Lastest Price from Bis-Propargyl-PEG4 manufacturers
- Product
- Bis-propargyl-PEG4 126422-58-0
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-26