Propargyl-PEG3-Sulfone-PEG3-Propargyl

Product Name: Propargyl-PEG3-Sulfone-PEG3-Propargyl
CAS No.: 2055024-44-5
Chemical Name: Propargyl-PEG3-Sulfone-PEG3-Propargyl
Synonyms: Propargyl-PEG3-Sulfone-PEG3-Propargyl;4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriaconta-1,30-diyne, 16,16-dioxide
CBNumber: CB93163107
Molecular Formula: C22H38O10S
Formula Weight: 494.6
MOL File: 2055024-44-5.mol

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Propargyl-PEG3-Sulfone-PEG3-Propargyl Property

Boiling point:: 591.6±50.0 °C(Predicted)
Density: 1.147±0.06 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23229
Product name: Propargyl-PEG3-Sulfone-PEG3-propargyl
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-23229
Product name: Propargyl-PEG3-Sulfone-PEG3-propargyl
Purity: 98%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-23229
Product name: Propargyl-PEG3-Sulfone-PEG3-propargyl
Purity: 98%
Packaging: 500mg
Price: $750
Updated: 2021/12/16

BroadPharm

Product number: BP-23229
Product name: Propargyl-PEG3-Sulfone-PEG3-propargyl
Purity: 98%
Packaging: 1g
Price: $1400
Updated: 2021/12/16

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Propargyl-PEG3-Sulfone-PEG3-Propargyl Chemical Properties,Usage,Production

Description

Propargyl-PEG3-Sulfone-PEG3-propargyl is a PEG linker containing two propargyl groups. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG spacer increases solubility in aqueous media.

Uses

Propargyl-peg3-sulfone-peg3-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-peg3-sulfone-peg3-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG3-Sulfone-PEG3-Propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG3-Sulfone-PEG3-Propargyl Suppliers

China 13 United States 2 Global 15

Xi'an Confluore Biological Technology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Taizhou Chuanxu Pharmaceutical Technology Co., Ltd.

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View Lastest Price from Propargyl-PEG3-Sulfone-PEG3-Propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG3-Sulfone-PEG3-propargyl 2055024-44-5
Price: US $0.00/mg
Min. Order: 500mg
Purity: >95.00%
Supply Ability: 500mg
Release date: 2024-03-28

2055024-44-5, Propargyl-PEG3-Sulfone-PEG3-PropargylRelated Search:

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Propargyl-PEG3-Sulfone-PEG3-Propargyl

4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriaconta-1,30-diyne, 16,16-dioxide

2055024-44-5