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Propargyl-PEG4-S-PEG4-Propargyl

Product Name
Propargyl-PEG4-S-PEG4-Propargyl
CAS No.
2055041-17-1
Chemical Name
Propargyl-PEG4-S-PEG4-Propargyl
Synonyms
Propargyl-PEG4-S-PEG4-Propargyl;4,7,10,13,19,22,25,28-Octaoxa-16-thiahentriaconta-1,30-diyne
CBNumber
CB63163111
Molecular Formula
C22H38O8S
Formula Weight
462.6
MOL File
2055041-17-1.mol
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23187
Product name
Propargyl-PEG4-S-PEG4-propargyl
Purity
98%
Packaging
100mg
Price
$280
Updated
2021/12/16
BroadPharm
Product number
BP-23187
Product name
Propargyl-PEG4-S-PEG4-propargyl
Purity
98%
Packaging
250mg
Price
$450
Updated
2021/12/16
BroadPharm
Product number
BP-23187
Product name
Propargyl-PEG4-S-PEG4-propargyl
Purity
98%
Packaging
500mg
Price
$680
Updated
2021/12/16
BroadPharm
Product number
BP-23187
Product name
Propargyl-PEG4-S-PEG4-propargyl
Purity
98%
Packaging
1g
Price
$1280
Updated
2021/12/16
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Propargyl-PEG4-S-PEG4-Propargyl Chemical Properties,Usage,Production

Description

Propargyl-PEG4-S-PEG4-propargyl is a PEG linker containing two propargyl groups. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydrophilic PEG chains increase the water solubility of the compound in aqueous media.

Uses

Propargyl-PEG4-S-PEG4-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG4-S-PEG4-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG4-S-PEG4-Propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG4-S-PEG4-Propargyl Suppliers

Xi'an Confluore Biological Technology Co., Ltd.
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+86-156-80926068 +86-15680926068
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1924344760@qq.com
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China
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4952
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58
Alpha Biopharmaceuticals Co., Ltd
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0411-39042497
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0411-39042693
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sales@alphabiopharm.com
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China
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1951
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58
TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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32435
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Nextpeptide Inc
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+86-0571-81612335 +8613336028439
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sales@nextpeptide.com
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China
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Zhengzhou Akem Chemical Co., Ltd
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13303867194
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3001317055@qq.com
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China
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9681
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
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psaitong@jm-bio.com
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China
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29757
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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd
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0431-80514535 19917294565
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et@chemextension.com
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China
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Shanghai Easy CDMO Co.,Ltd
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021-61734564 13854185395;
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info@easycdmo.com
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China
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10024
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shanghai Yanfeng biochemical technology Co.,LTD
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17721070236 13611955358;
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yanfen2023@126.com
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China
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2393
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Jilin Chinese Academy of Sciences-yanshen Technology
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18143011203
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ET-market@chemextension.com
Country
China
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32034
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58
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View Lastest Price from Propargyl-PEG4-S-PEG4-Propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG4-S-PEG4-propargyl 2055041-17-1
Price
US $0.00/mg
Min. Order
500mg
Purity
>95.00%
Supply Ability
500mg
Release date
2024-03-28