Propargyl-PEG1-SS-alcohol

Product Name: Propargyl-PEG1-SS-alcohol
CAS No.: 1391914-41-2
Chemical Name: Propargyl-PEG1-SS-alcohol
Synonyms: Propargyl-PEG1-SS-alcohol;Ethanol, 2-[[2-(2-propyn-1-yloxy)ethyl]dithio]-;2-((2-(Prop-2-yn-1-yloxy)ethyl)disulfaneyl)ethan-1-ol
CBNumber: CB53062613
Molecular Formula: C7H12O2S2
Formula Weight: 192.3
MOL File: 1391914-41-2.mol

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P839565
Product name: Propargyl-PEG1-SS-alcohol
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-22670
Product name: Propargyl-PEG1-SS-alcohol
Purity: 98%
Packaging: 250mg
Price: $430
Updated: 2021/12/16

BroadPharm

Product number: BP-22670
Product name: Propargyl-PEG1-SS-alcohol
Purity: 98%
Packaging: 500mg
Price: $680
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1739
Product name: Propargyl-PEG1-SS-alcohol
Packaging: 250mg
Price: $837
Updated: 2021/12/16

BroadPharm

Product number: BP-22670
Product name: Propargyl-PEG1-SS-alcohol
Purity: 98%
Packaging: 1g
Price: $1020
Updated: 2021/12/16

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Propargyl-PEG1-SS-alcohol Chemical Properties,Usage,Production

Description

Propargyl-PEG1-SS-alcohol is a Click Chemistry-ready crosslinker containing a propargyl group, a hydroxyl group and a cleavable disulfide bond. The propargyl groups can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.

Uses

Propargyl-PEG1-SS-alcohol is a cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-alcohol is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Propargyl-PEG1-SS-alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG1-SS-alcohol Suppliers

China 35 United Kingdom 1 United States 4 Global 40

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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View Lastest Price from Propargyl-PEG1-SS-alcohol manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG1-SS-alcohol 1391914-41-2
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-21

1391914-41-2, Propargyl-PEG1-SS-alcoholRelated Search:

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Propargyl-PEG1-SS-alcohol

Ethanol, 2-[[2-(2-propyn-1-yloxy)ethyl]dithio]-

2-((2-(Prop-2-yn-1-yloxy)ethyl)disulfaneyl)ethan-1-ol

1391914-41-2