Propargyl-PEG1-SS-PEG1-propargyl

Product Name: Propargyl-PEG1-SS-PEG1-propargyl
CAS No.: 1964503-40-9
Chemical Name: Propargyl-PEG1-SS-PEG1-propargyl
Synonyms: Propargyl-PEG1-SS-PEG1-propargy;Propargyl-PEG1-SS-PEG1-propargyl;Disulfide, bis[2-(2-propyn-1-yloxy)ethyl]-;1,2-bis(2-(prop-2-yn-1-yloxy)ethyl)disulfane
CBNumber: CB73363989
Molecular Formula: C10H14O2S2
Formula Weight: 230.35
MOL File: 1964503-40-9.mol

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Propargyl-PEG1-SS-PEG1-propargyl Property

Boiling point:: 326.0±37.0 °C(Predicted)
Density: 1.141±0.06 g/cm3(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23283
Product name: Propargyl-PEG1-SS-PEG1-propargyl
Purity: 98%
Packaging: 250mg
Price: $350
Updated: 2021/12/16

BroadPharm

Product number: BP-23283
Product name: Propargyl-PEG1-SS-PEG1-propargyl
Purity: 98%
Packaging: 500mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-23283
Product name: Propargyl-PEG1-SS-PEG1-propargyl
Purity: 98%
Packaging: 1g
Price: $750
Updated: 2021/12/16

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Propargyl-PEG1-SS-PEG1-propargyl Chemical Properties,Usage,Production

Description

Propargyl-PEG1-SS-PEG1-propargyl is a homoebifunctional cleavable PEG linker containing two propargyl groups and a disulfide bond. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. Disulfide bond cn be cleaved with reducing agent.

Uses

Propargyl-PEG1-SS-PEG1-propargyl is a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Disulfide Cleavable Linker; Cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268

Propargyl-PEG1-SS-PEG1-propargyl Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG1-SS-PEG1-propargyl Suppliers

China 21 United States 4 Global 25

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
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Jinan elephant international trading co., LTD

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Beijing Jin Ming Biotechnology Co., Ltd.

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Xi'an Confluore Biological Technology Co., Ltd.

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
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Hangzhou Huarong Pharm Co., Ltd.

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Shaanxi Xinyan Bomei Biotechnology Co., Ltd.

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Hangzhou Taorui Biotechnology Co., Ltd

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Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

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Zhengzhou Akem Chemical Co., Ltd

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View Lastest Price from Propargyl-PEG1-SS-PEG1-propargyl manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG1-SS-PEG1-propargyl 1964503-40-9
Price: US $0.00/mg
Min. Order: 100mg
Purity: >95.00%
Supply Ability: 100mg
Release date: 2024-03-21

1964503-40-9, Propargyl-PEG1-SS-PEG1-propargylRelated Search:

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Propargyl-PEG1-SS-PEG1-propargyl

Disulfide, bis[2-(2-propyn-1-yloxy)ethyl]-

1,2-bis(2-(prop-2-yn-1-yloxy)ethyl)disulfane

Propargyl-PEG1-SS-PEG1-propargy

1964503-40-9