Propargyl-PEG1-t-butyl ester

Product Name: Propargyl-PEG1-t-butyl ester
CAS No.: 488150-84-1
Chemical Name: Propargyl-PEG1-t-butyl ester
Synonyms: Propargyl-PEG1-Boc;Propargyl-PEG1-COOtBu;Alkyne-PEG1-CH2CH2COOtBu;PROPARGYL-PEG1-CH2CH2COOTBU;Propargyl-PEG1-t-butyl ester;tert-butyl 3-prop-2-ynoxypropanoate;tert-Butyl 3-(2-Propyn-1-yloxy)propanoate;3-(2-Propyn-1-yloxy)propanoic acid tert-butyl ester;Propanoic acid, 3-(2-propyn-1-yloxy)-, 1,1-dimethylethyl ester
CBNumber: CB43062616
Molecular Formula: C10H16O3
Formula Weight: 184.23
MOL File: 488150-84-1.mol

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Propargyl-PEG1-t-butyl ester Property

storage temp.: Storage temp. 2-8°C
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C10H16O3/c1-5-7-12-8-6-9(11)13-10(2,3)4/h1H,6-8H2,2-4H3
InChIKey: VDHVLESCKRSEAF-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCC#C

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: P839875
Product name: Propargyl-PEG1-t-butylester
Packaging: 50mg
Price: $220
Updated: 2021/12/16

TRC

Product number: P839875
Product name: Propargyl-PEG1-t-butylester
Packaging: 5mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-21980
Product name: Propargyl-PEG1-t-butylester
Purity: 98%
Packaging: 500mg
Price: $480
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1742
Product name: Propargyl-PEG1-t-butyl ester
Packaging: 250mg
Price: $546
Updated: 2021/12/16

Activate Scientific

Product number: AS107422
Product name: 3-(2-Propyn-1-yloxy)propanoicacidtert-butylester
Purity: 97%
Packaging: 250mg
Price: $215
Updated: 2021/12/16

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Propargyl-PEG1-t-butyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG1-t-butyl ester has a propargyl group and a t-butyl protected carboxyl group. The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG1-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG1-t-butyl ester Suppliers

China 42 India 1 United Kingdom 1 United States 3 Global 47

Hunan HuaTeng Pharmaceutical Co., Ltd.,

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Shanghai alkynechem Co., Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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View Lastest Price from Propargyl-PEG1-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Propargyl-PEG1-COOtBu 488150-84-1
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-26

488150-84-1, Propargyl-PEG1-t-butyl esterRelated Search:

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Propargyl-PEG1-t-butyl ester

Alkyne-PEG1-CH2CH2COOtBu

PROPARGYL-PEG1-CH2CH2COOTBU

3-(2-Propyn-1-yloxy)propanoic acid tert-butyl ester

Propargyl-PEG1-COOtBu

Propargyl-PEG1-Boc

Propanoic acid, 3-(2-propyn-1-yloxy)-, 1,1-dimethylethyl ester

tert-butyl 3-prop-2-ynoxypropanoate

tert-Butyl 3-(2-Propyn-1-yloxy)propanoate

488150-84-1

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