Propargyl-PEG1-SS-PEG1-t-butyl ester
- Product Name
- Propargyl-PEG1-SS-PEG1-t-butyl ester
- CAS No.
- 1807518-78-0
- Chemical Name
- Propargyl-PEG1-SS-PEG1-t-butyl ester
- Synonyms
- ropargyl-PEG1-SS-PEG1-C2-Boc;Propargyl-PEG1-SS-PEG1-C2-Boc;Propargyl-PEG1-SS-PEG1-t-butyl ester;tert-Butyl 3-[2-[[2-(Prop-2-yn-1-yloxy)ethyl]disulfanyl]ethoxy]propanoate;tert-Butyl 3-(2-((2-(prop-2-yn-1-yloxy)ethyl)disulfaneyl)ethoxy)propanoate;Propanoic acid, 3-[2-[[2-(2-propyn-1-yloxy)ethyl]dithio]ethoxy]-, 1,1-dimethylethyl ester
- CBNumber
- CB13062615
- Molecular Formula
- C14H24O4S2
- Formula Weight
- 320.47
- MOL File
- 1807518-78-0.mol
Propargyl-PEG1-SS-PEG1-t-butyl ester Property
- Boiling point:
- 407.4±40.0 °C(Predicted)
- Density
- 1.114±0.06 g/cm3(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- BP-22669
- Product name
- Propargyl-PEG1-SS-PEG1-t-butylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- BIPG1741
- Product name
- Propargyl-PEG1-SS-PEG1-t-butyl ester
- Packaging
- 100mg
- Price
- $565
- Updated
- 2021/12/16
- Product number
- BP-22669
- Product name
- Propargyl-PEG1-SS-PEG1-t-butylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $680
- Updated
- 2021/12/16
Propargyl-PEG1-SS-PEG1-t-butyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG1-SS-PEG1-t-butyl ester is a Click Chemistry crosslinker containing a propargyl group that can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield stable triazole linkages. The t-butyl protected carboxyl group prevents self coupling or polymerization under standard acid/amine or acid/hydroxyl coupling condition, t-butyl can be deprotected under acidic conditions.
Uses
Propargyl-PEG1-SS-PEG1-C2-Boc is a Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs. Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Propargyl-PEG1-SS-PEG1-C2-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
Cleavable Linker; Disulfide Cleavable Linker; Alkyl/ether
References
[1] Barrientos AG, et al. Gold glyconanoparticles: synthetic polyvalent ligands mimicking glycocalyx-like surfaces as tools for glycobiological studies. Chemistry. 2003 May 9;9(9):1909-21. DOI:10.1002/chem.200204544
Propargyl-PEG1-SS-PEG1-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG1-SS-PEG1-t-butyl ester Suppliers
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View Lastest Price from Propargyl-PEG1-SS-PEG1-t-butyl ester manufacturers
- Product
- Propargyl-PEG1-SS-PEG1-t-butyl ester 1807518-78-0
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >95.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-21