ChemicalBook > CAS DataBase List > Propargyl-PEG1-t-butyl ester

Propargyl-PEG1-t-butyl ester

Product Name
Propargyl-PEG1-t-butyl ester
CAS No.
488150-84-1
Chemical Name
Propargyl-PEG1-t-butyl ester
Synonyms
Propargyl-PEG1-Boc;Propargyl-PEG1-COOtBu;Alkyne-PEG1-CH2CH2COOtBu;PROPARGYL-PEG1-CH2CH2COOTBU;Propargyl-PEG1-t-butyl ester;tert-butyl 3-prop-2-ynoxypropanoate;tert-Butyl 3-(2-Propyn-1-yloxy)propanoate;3-(2-Propyn-1-yloxy)propanoic acid tert-butyl ester;Propanoic acid, 3-(2-propyn-1-yloxy)-, 1,1-dimethylethyl ester
CBNumber
CB43062616
Molecular Formula
C10H16O3
Formula Weight
184.23
MOL File
488150-84-1.mol
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Propargyl-PEG1-t-butyl ester Property

storage temp. 
Storage temp. 2-8°C
form 
Liquid
color 
Colorless to light yellow
InChI
InChI=1S/C10H16O3/c1-5-7-12-8-6-9(11)13-10(2,3)4/h1H,6-8H2,2-4H3
InChIKey
VDHVLESCKRSEAF-UHFFFAOYSA-N
SMILES
C(OC(C)(C)C)(=O)CCOCC#C
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P839875
Product name
Propargyl-PEG1-t-butylester
Packaging
50mg
Price
$220
Updated
2021/12/16
TRC
Product number
P839875
Product name
Propargyl-PEG1-t-butylester
Packaging
5mg
Price
$45
Updated
2021/12/16
BroadPharm
Product number
BP-21980
Product name
Propargyl-PEG1-t-butylester
Purity
98%
Packaging
500mg
Price
$480
Updated
2021/12/16
Apolloscientific
Product number
BIPG1742
Product name
Propargyl-PEG1-t-butyl ester
Packaging
250mg
Price
$546
Updated
2021/12/16
Activate Scientific
Product number
AS107422
Product name
3-(2-Propyn-1-yloxy)propanoicacidtert-butylester
Purity
97%
Packaging
250mg
Price
$215
Updated
2021/12/16
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Propargyl-PEG1-t-butyl ester Chemical Properties,Usage,Production

Description

Propargyl-PEG1-t-butyl ester has a propargyl group and a t-butyl protected carboxyl group. The propargyl group can participate in copper catalyzed azide-alkyne Click Chemistry to form a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Propargyl-PEG1-Boc is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG1-Boc is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Propargyl-PEG1-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Propargyl-PEG1-t-butyl ester Suppliers

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View Lastest Price from Propargyl-PEG1-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Propargyl-PEG1-COOtBu 488150-84-1
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-26

488150-84-1, Propargyl-PEG1-t-butyl esterRelated Search:

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