Dde Biotin-PEG4-Alkyne

Product Name: Dde Biotin-PEG4-Alkyne
CAS No.: 1802908-00-4
Chemical Name: Dde Biotin-PEG4-Alkyne
Synonyms: Dde Biotin-PEG4-Alkyne;Biotin-peg(4)-dde-alkyne;Dde Biotin-PEG4-alkyne Dde;1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl]hexahydro-2-oxo-, (3aR,4R,6aS)-rel-
CBNumber: CB43062469
Molecular Formula: C32H50N4O8S
Formula Weight: 650.83
MOL File: 1802908-00-4.mol

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Dde Biotin-PEG4-Alkyne Property

Boiling point:: 880.0±65.0 °C(Predicted)
Density: 1.173±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Solid
pka: 13.90±0.40(Predicted)
color: Brown to reddish brown

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22679
Product name: DdeBiotin-PEG4-alkyne
Purity: 95%
Packaging: 5mg
Price: $239
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG7980
Product name: Biotin-PEG(4)-Dde-Alkyne
Packaging: 10mg
Price: $337.5
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG7980
Product name: Biotin-PEG(4)-Dde-Alkyne
Packaging: 25mg
Price: $560.25
Updated: 2021/12/16

Iris Biotech GmbH

Product number: PEG7980
Product name: Biotin-PEG(4)-Dde-Alkyne
Packaging: 100mg
Price: $1687.5
Updated: 2021/12/16

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Dde Biotin-PEG4-Alkyne Chemical Properties,Usage,Production

Description

Dde Biotin-PEG4-alkyne is useful for introducing a biotin moiety to azide-containing molecules using Cu(I)-catalyzed Click Chemistry. The hydrophilic spacer arm provides better solubility to the labeled molecules in aqueous media. Dde protecting group allows efficient release of captured biotinylated molecules from streptavidin under mild conditions with hydrazine.

Uses

Dde Biotin-PEG4-alkyne is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Dde Biotin-PEG4-alkyne is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Dde Biotin-PEG4-Alkyne Preparation Products And Raw materials

Raw materials

Preparation Products

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Dde Biotin-PEG4-Alkyne Suppliers

China 23 United States 4 Global 27

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
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Advantage: 58

Jinan elephant international trading co., LTD

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Email: 13006575422@163.com
Country: China
ProdList: 6355
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
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Shanghai Hongye Biotechnology Co. Ltd

Tel: 400-9205774
Email: sales@glpbio.cn
Country: China
ProdList: 6777
Advantage: 58

Alfa Chemistry

Tel: +1-5166625404;
Fax: 1-516-927-0118
Email: Info@alfa-chemistry.com
Country: United States
ProdList: 20405
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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
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Taizhou Nanfeng Pharmaceutical Research Institute

Tel: nanfengdrug@163.com; 18616377689
Email: nanfengdrug@163.com
Country: China
ProdList: 20009
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Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 4008210725
Email: malulu@leyan.com
Country: China
ProdList: 55000
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Hangzhou Taorui Biotechnology Co., Ltd

Tel: 4000-360-990 15268198094
Email: sales@torreybio.com
Country: China
ProdList: 3806
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Zhengzhou Akem Chemical Co., Ltd

Tel: 13303867194
Email: 3001317055@qq.com
Country: China
ProdList: 9681
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View Lastest Price from Dde Biotin-PEG4-Alkyne manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Dde Biotin-PEG4-alkyne 1802908-00-4
Price: US $0.00/mg
Min. Order: 50mg
Purity: >99.00%
Supply Ability: 50mg
Release date: 2024-03-21

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Biotin-peg(4)-dde-alkyne

Dde Biotin-PEG4-Alkyne

1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[15-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3,6,9,12-tetraoxa-16-azanonadec-18-yn-1-yl]hexahydro-2-oxo-, (3aR,4R,6aS)-rel-

Dde Biotin-PEG4-alkyne Dde

1802908-00-4

C32H50N4O8S