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Methyltetrazine-PEG4-Amine

Product Name
Methyltetrazine-PEG4-Amine
CAS No.
1802908-05-9
Chemical Name
Methyltetrazine-PEG4-Amine
Synonyms
Methyltetrazine-PEG4-Amine;Methyltetrazine-PEG4-amine HCl salt;Methyltetrazine-PEG4-Amine (CCT-1012);3-[4-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)phenyl]-6-methyl-1,2,4,5-tetrazine;2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethanamine;Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-
CBNumber
CB43345052
Molecular Formula
C17H25N5O4
Formula Weight
363.41
MOL File
1802908-05-9.mol
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Methyltetrazine-PEG4-Amine Property

Boiling point:
558.7±60.0 °C(Predicted)
Density 
1.186±0.06 g/cm3(Predicted)
solubility 
Soluble in Water, DMSO, DMF, DCM
pka
8.74±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-22435
Product name
Methyltetrazine-PEG4-amineHClsalt
Purity
95%
Packaging
25mg
Price
$95
Updated
2021/12/16
Chem-Impex
Product number
35097
Product name
Methyltetrazine-PEG4-amine,95%(HPLC)
Purity
95%(HPLC)
Packaging
25MG
Price
$175.56
Updated
2021/12/16
Iris Biotech GmbH
Product number
RL-2370
Product name
MeTz-PEG(4)-NH2*HCl
Packaging
25mg
Price
$229.5
Updated
2021/12/16
Chem-Impex
Product number
35097
Product name
Methyltetrazine-PEG4-amine,95%(HPLC)
Purity
95%(HPLC)
Packaging
100MG
Price
$457.52
Updated
2021/12/16
Chem-Impex
Product number
35097
Product name
Methyltetrazine-PEG-amine
Purity
≥ 95% (HPLC)
Packaging
250MG
Price
$540
Updated
2021/12/16
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Methyltetrazine-PEG4-Amine Chemical Properties,Usage,Production

Description

Methyltetrazine-PEG4-amine is an aqueous soluble PEGylation reagent containing a free amine and a methyltetrazine group. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).

Uses

Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyltetrazine-PEG4-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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Methyltetrazine-PEG4-Amine Suppliers

Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
400-6206333 13167063860
Fax
021-50323701
Email
anhua.mao@aladdin-e.com
Country
China
ProdList
25003
Advantage
65
Shanghai Send Pharmaceutical Technology Co., Ltd.
Tel
021-58088081 Q2635253576
Fax
QQ3382968513
Email
hailey@shsendpharm.com
Country
China
ProdList
2081
Advantage
55
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
Advantage
55
Jinan elephant international trading co., LTD
Tel
Fax
-
Email
13006575422@163.com
Country
China
ProdList
6355
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
Advantage
58
Henan Alfachem Co.,Ltd.
Tel
0371-55051623 18137891487
Fax
QQ:2853979817
Email
2853979817@qq.com
Country
China
ProdList
9984
Advantage
58
Henan's chemical products co., LTD
Tel
0371-60919097 15378766539
Fax
0371-60919097
Email
794449696@qq.com
Country
China
ProdList
4996
Advantage
58
Alfa Chemistry
Tel
+1-5166625404;
Fax
1-516-927-0118
Email
Info@alfa-chemistry.com
Country
United States
ProdList
20405
Advantage
58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32435
Advantage
58
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View Lastest Price from Methyltetrazine-PEG4-Amine manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Methyltetrazine-PEG4-amine HCl salt 1802908-05-9
Price
US $0.00/mg
Min. Order
25mg
Purity
>99.00%
Supply Ability
100mg
Release date
2024-03-20

1802908-05-9, Methyltetrazine-PEG4-AmineRelated Search:


  • Methyltetrazine-PEG4-Amine
  • Methyltetrazine-PEG4-amine HCl salt
  • Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-
  • 2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethanamine
  • 3-[4-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)phenyl]-6-methyl-1,2,4,5-tetrazine
  • Methyltetrazine-PEG4-Amine (CCT-1012)
  • 1802908-05-9
  • 1802908-95-9