Methyltetrazine-PEG4-Amine

Product Name: Methyltetrazine-PEG4-Amine
CAS No.: 1802908-05-9
Chemical Name: Methyltetrazine-PEG4-Amine
Synonyms: Methyltetrazine-PEG4-Amine;Methyltetrazine-PEG4-amine HCl salt;Methyltetrazine-PEG4-Amine (CCT-1012);3-[4-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)phenyl]-6-methyl-1,2,4,5-tetrazine;2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethanamine;Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-
CBNumber: CB43345052
Molecular Formula: C17H25N5O4
Formula Weight: 363.41
MOL File: 1802908-05-9.mol

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Methyltetrazine-PEG4-Amine Property

Boiling point:: 558.7±60.0 °C(Predicted)
Density: 1.186±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DMF, DCM
pka: 8.74±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22435
Product name: Methyltetrazine-PEG4-amineHClsalt
Purity: 95%
Packaging: 25mg
Price: $95
Updated: 2021/12/16

Chem-Impex

Product number: 35097
Product name: Methyltetrazine-PEG4-amine,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 25MG
Price: $175.56
Updated: 2021/12/16

Iris Biotech GmbH

Product number: RL-2370
Product name: MeTz-PEG(4)-NH2*HCl
Packaging: 25mg
Price: $229.5
Updated: 2021/12/16

Chem-Impex

Product number: 35097
Product name: Methyltetrazine-PEG4-amine,95%(HPLC)
Purity: 95%(HPLC)
Packaging: 100MG
Price: $457.52
Updated: 2021/12/16

Chem-Impex

Product number: 35097
Product name: Methyltetrazine-PEG-amine
Purity: ≥ 95% (HPLC)
Packaging: 250MG
Price: $540
Updated: 2021/12/16

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Methyltetrazine-PEG4-Amine Chemical Properties,Usage,Production

Description

Methyltetrazine-PEG4-amine is an aqueous soluble PEGylation reagent containing a free amine and a methyltetrazine group. Methyl group improves the stability and hydrophilic PEG spacer increases water-solubility. Methyltetrazine enable fast click reaction with TCO (trans-cycloctene).

Uses

Methyltetrazine-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Methyltetrazine-PEG4-Amine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Methyltetrazine-PEG4-Amine manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Methyltetrazine-PEG4-amine HCl salt 1802908-05-9
Price: US $0.00/mg
Min. Order: 25mg
Purity: >99.00%
Supply Ability: 100mg
Release date: 2024-03-20

1802908-05-9, Methyltetrazine-PEG4-AmineRelated Search:

Methyltetrazine-PEG4-Acid N-[2-[2-[2-[2-(Aminooxy)ethoxy]ethoxy]ethoxy]ethoxy]-4-(6-methyl-1,2,4,5-tetrazin-3-yl)benzeneacetamide Me-Tet-PEG4-NH2 Tetrazine-PEG4-amine HCl salt Methyltetrazine-propylamine HCl salt TAMRA-PEG4-Tetrazine Methyltetrazine-PEG4-Alkyne Methyltetrazine-PEG4-Azide Desthiobiotin-PEG4-Alkyne Tetrazine-PEG4-maleimide Dde Biotin-PEG4-Alkyne Methyltetrazine-PEG5-Alkyne Dde Biotin-PEG4-Azide Bis-sulfone-PEG3-Azide Methyltetrazine-PEG4-NHS Ester

Methyltetrazine-PEG4-Amine

Methyltetrazine-PEG4-amine HCl salt

Ethanamine, 2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]-

2-(2-(2-(2-(4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy)ethoxy)ethoxy)ethoxy)ethanamine

3-[4-(2-{2-[2-(2-aminoethoxy)ethoxy]ethoxy}ethoxy)phenyl]-6-methyl-1,2,4,5-tetrazine

Methyltetrazine-PEG4-Amine (CCT-1012)

1802908-05-9

1802908-95-9