Azido-PEG4-CH2CO2H

Product Name: Azido-PEG4-CH2CO2H
CAS No.: 1694731-93-5
Chemical Name: Azido-PEG4-CH2CO2H
Synonyms: Propargyl-PEG4;AZIDE-PEG4-CH2COOH;Azido-PEG4-CH2COOH;Azido-PEG4-CH2CO2H;Alkyne-PEG3-CH2COOH;Propargyl-PEG3-CH2COOH;Propargyl-PEG3-acetic Acid;3,6,9,12-Tetraoxapentadec-14-ynoic acid;3,6,9,12-tetraoxapentadec-14-yn-1-ic acid;2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]acetic acid
CBNumber: CB93062358
Molecular Formula: C11H18O6
Formula Weight: 246.26
MOL File: 1694731-93-5.mol

More

Less

Azido-PEG4-CH2CO2H Property

Boiling point:: 375.0±32.0 °C(Predicted)
Density: 1.151±0.06 g/cm3(Predicted)
storage temp.: Store at 0-8 °C
pka: 3.39±0.10(Predicted)
form: Liquid
color: Light yellow to yellow
InChI: InChI=1S/C11H18O6/c1-2-3-14-4-5-15-6-7-16-8-9-17-10-11(12)13/h1H,3-10H2,(H,12,13)
InChIKey: MJRNNISHHNMYAE-UHFFFAOYSA-N
SMILES: C(O)(=O)COCCOCCOCCOCC#C

More

Less

Safety

HS Code: 2918999090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More

Less

N-Bromosuccinimide Price

Activate Scientific

Product number: AS103930
Product name: Propargyl-PEG3-CH2COOH
Purity: 95+%
Packaging: 1g
Price: $602
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1144
Product name: Azido-PEG4-CH2CO2H
Packaging: 100mg
Price: $623
Updated: 2021/12/16

BroadPharm

Product number: BP-22737
Product name: Propargyl-PEG4-CH2CO2H
Purity: 98%
Packaging: 500mg
Price: $650
Updated: 2021/12/16

BroadPharm

Product number: BP-22737
Product name: Propargyl-PEG4-CH2CO2H
Purity: 98%
Packaging: 1g
Price: $980
Updated: 2021/12/16

BroadPharm

Product number: BP-22737
Product name: Propargyl-PEG4-CH2CO2H
Purity: 98%
Packaging: 100mg
Price: $250
Updated: 2021/12/16

More

Less

Azido-PEG4-CH2CO2H Chemical Properties,Usage,Production

Description

Propargyl-PEG4-CH2CO2H is a linker consisting of a propargyl group with a carboxylic acid group. The carboxylic acid can react with primary amine groups in the presence of activators such as HATU or EDC. The propargyl group can react with azide compounds in Click Chemistry; copper catalyst will be needed. The PEG units help the molecule to have better solubility in aqueous solution.

Uses

Propargyl-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-CH2COOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Wurz RP, et al. A "Click Chemistry Platform" for the Rapid Synthesis of Bispecific Molecules for Inducing ProteinDegradation. J Med Chem. 2018 Jan 25;61(2):453-461. DOI:10.1021/acs.jmedchem.6b01781

Azido-PEG4-CH2CO2H Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Azido-PEG4-CH2CO2H Suppliers

China 58 United States 3 Global 61

Henan Weitixi Chemical Technology Co., Ltd

Tel: 0371-53370800 18037197114
Email: 2853031799@qq.com
Country: China
ProdList: 9892
Advantage: 58

T&W GROUP

Tel: 021-61551611 13296011611
Fax: ＋86 21-50676805
Email: contact@trustwe.com
Country: China
ProdList: 9895
Advantage: 58

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-0431-80514535 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3935
Advantage: 55

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
Advantage: 55

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
Fax: -
Email: sales09@leobiochem.com
Country: China
ProdList: 433
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9713
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32435
Advantage: 58

1694731-93-5, Azido-PEG4-CH2CO2HRelated Search:

Propargyl-PEG4-thiol 5-(9-FLUORENYLMETHYLOXYCARBONYL-AMINO)-3-OXAPENTANOIC ACID Propargyl-PEG4-CH2CO2-NHS Propargyl-PEG5-beta-D-galactose Propargyl-PEG4-CH2CO2tBu Propargyl-PEG5-tetra-Ac-beta-D-galactose Propargyl-PEG4-S-PEG4-t-butyl ester Propargyl-PEG4-acid Propargyl-PEG4-S-PEG4-Propargyl Propargyl-PEG4-Sulfone-PEG4-t-butyl ester Propargyl-PEG4-S-PEG4-acid Propargyl-PEG4-bromide Propargyl-PEG4-t-butyl ester Propargyl-PEG4-Sulfone-PEG4-acid Propargyl-PEG4-methylamine Propargyl-PEG3-Tos Propargyl-PEG4-sulfonic acid Azido-PEG12-t-butyl ester

Azido-PEG4-CH2CO2H

Azido-PEG4-CH2COOH

AZIDE-PEG4-CH2COOH

Propargyl-PEG3-CH2COOH

Propargyl-PEG4

3,6,9,12-Tetraoxapentadec-14-ynoic acid

3,6,9,12-tetraoxapentadec-14-yn-1-ic acid

Propargyl-PEG3-CH2COOH/3,6,9,12-Tetraoxapentadec-14-ynoic acid

2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]acetic acid

Alkyne-PEG3-CH2COOH

Propargyl-PEG3-acetic Acid

1694731-93-5

peg