Propargyl-PEG4-CH2CO2-NHS
- Product Name
- Propargyl-PEG4-CH2CO2-NHS
- CAS No.
- 2144777-76-2
- Chemical Name
- Propargyl-PEG4-CH2CO2-NHS
- Synonyms
- Propargyl-PEG3-CH2COONHS;Propargyl-PEG4-CH2CO2-NHS;Propargyl-PEG3-CH2CONHS ester;Propargyl-PEG3-O-CH2-NHS ester;Propargyl-PEG4-CH2COO-NHS ester;Propargyl-PEG4-CH2COOH NHS Ester;2,5-dioxopyrrolidin-1-yl 3,6,9,12-tetraoxapentadec-14-ynoate;3,6,9,12-Tetraoxapentadec-14-ynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
- CBNumber
- CB94849646
- Molecular Formula
- C15H21NO8
- Formula Weight
- 343.33
- MOL File
- 2144777-76-2.mol
Propargyl-PEG4-CH2CO2-NHS Property
- solubility
- Soluble in DMSO, DCM, DMF
N-Bromosuccinimide Price
- Product number
- BP-23811
- Product name
- Propargyl-PEG4-CH2CO2-NHS
- Packaging
- 500mg
- Price
- $650
- Updated
- 2021/12/16
Propargyl-PEG4-CH2CO2-NHS Chemical Properties,Usage,Production
Description
Propargyl-PEG4-CH2CO2-NHS has a propargyl group and an NHS group. This reagent is amine reactive, thus, useful for derivatizing biomolecules with amine group. The propargyl group reacts with azides via copper catalyzed azide-alkyne Click Chemistry to form stable triazole bond.
Uses
Propargyl-PEG4-CH2CO2-NHS (compound P-7) is a PEG derivative containing a propargyl group and an NHS group. Propargyl-PEG4-CH2CO2-NHS is an ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Propargyl-PEG4-CH2CO2-NHS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups[1].
References
[1] Woo Sung-ho, et al. Composé comprenant un groupe auto-immolable et conjugué ligand-médicament le comprenant. WO2024005460A1.
Propargyl-PEG4-CH2CO2-NHS Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG4-CH2CO2-NHS Suppliers
- Tel
- 021-61551611 13296011611
- Fax
- ＋86 21-50676805
- contact@trustwe.com
- Country
- China
- ProdList
- 9895
- Advantage
- 58
- Tel
- 0431-0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 3935
- Advantage
- 55
- Tel
- +1-5166625404;
- Fax
- 1-516-927-0118
- Info@alfa-chemistry.com
- Country
- United States
- ProdList
- 20405
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- 13892832556
- 2440688701@qq.com
- Country
- China
- ProdList
- 1994
- Advantage
- 58
- Tel
- +86-021-61551413 +8618813727289
- contact@trustwe.com
- Country
- China
- ProdList
- 5743
- Advantage
- 58
- Tel
- 13303867194
- 3001317055@qq.com
- Country
- China
- ProdList
- 9681
- Advantage
- 58
- Tel
- 15841022315
- sales@affinitytech.cn
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 5061
- Advantage
- 58
- Tel
- 15366892466
- greenchem@tzglmk.com
- Country
- China
- ProdList
- 1028
- Advantage
- 58