Propargyl--PEG3-phosphonic acid
- Product Name
- Propargyl--PEG3-phosphonic acid
- CAS No.
- 1714139-62-4
- Chemical Name
- Propargyl--PEG3-phosphonic acid
- Synonyms
- Propargyl--PEG3-phosphonic acid;(2-(2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethoxy)ethyl)phosphonic acid;Phosphonic acid, P-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethyl]-
- CBNumber
- CB63163106
- Molecular Formula
- C9H17O6P
- Formula Weight
- 252.2
- MOL File
- 1714139-62-4.mol
Propargyl--PEG3-phosphonic acid Property
- Boiling point:
- 417.2±55.0 °C(Predicted)
- Density
- 1.266±0.06 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM
- pka
- 2.14±0.10(Predicted)
N-Bromosuccinimide Price
- Product number
- BP-23272
- Product name
- Propargyl-PEG3-phosphonicacid
- Purity
- 98%
- Packaging
- 100mg
- Price
- $380
- Updated
- 2021/12/16
- Product number
- BP-23272
- Product name
- Propargyl-PEG3-phosphonicacid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- BP-23272
- Product name
- Propargyl-PEG3-phosphonicacid
- Purity
- 98%
- Packaging
- 500mg
- Price
- $975
- Updated
- 2021/12/16
Propargyl--PEG3-phosphonic acid Chemical Properties,Usage,Production
Description
Propargyl-PEG3-phosphonic acid is a crosslinker containing a propargyl group and a phosphonic acid. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Propargyl-PEG3-phosphonic acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-phosphonic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Thorsten Heidelberg, et al. Oligo-ethylene glycol based phosphonate surface modification reagents and use thereof. WO2015065168A1.
Propargyl--PEG3-phosphonic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Propargyl--PEG3-phosphonic acid manufacturers
- Product
- Propargyl-PEG3-phosphonic acid 1714139-62-4
- Price
- US $0.00/mg
- Min. Order
- 100mg
- Purity
- >98.00%
- Supply Ability
- 100mg
- Release date
- 2024-03-26