Propargyl-PEG3-Ms
- Product Name
- Propargyl-PEG3-Ms
- CAS No.
- 943726-01-0
- Chemical Name
- Propargyl-PEG3-Ms
- Synonyms
- Propargyl-PEG2-Ms;Propargyl-PEG3-Ms;2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate;2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate;2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate - [P88013];Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-methanesulfonate
- CBNumber
- CB03062623
- Molecular Formula
- C8H14O5S
- Formula Weight
- 222.26
- MOL File
- 943726-01-0.mol
Propargyl-PEG3-Ms Property
- storage temp.
- Storage temp. 2-8°C
- form
- Liquid
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-22921
- Product name
- Propargyl-PEG3-Ms
- Purity
- 98%
- Packaging
- 500mg
- Price
- $680
- Updated
- 2021/12/16
Propargyl-PEG3-Ms Chemical Properties,Usage,Production
Description
Propargyl-PEG3-Ms is a crosslinking reagent with a propargyl group and a mesyl group. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.
Uses
Propargyl-PEG2-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Bai S, et al. Synthesis and structure-activity relationship studies of conformationally flexibletetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands. J Med Chem. 2014 May 22;57(10):4239-51. DOI:10.1021/jm5001453
Propargyl-PEG3-Ms Preparation Products And Raw materials
Raw materials
Preparation Products
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