Propargyl-PEG3-Ms

Product Name: Propargyl-PEG3-Ms
CAS No.: 943726-01-0
Chemical Name: Propargyl-PEG3-Ms
Synonyms: Propargyl-PEG2-Ms;Propargyl-PEG3-Ms;2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate;2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate;2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate - [P88013];Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-methanesulfonate
CBNumber: CB03062623
Molecular Formula: C8H14O5S
Formula Weight: 222.26
MOL File: 943726-01-0.mol

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Propargyl-PEG3-Ms Property

storage temp.: Storage temp. 2-8°C
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22921
Product name: Propargyl-PEG3-Ms
Purity: 98%
Packaging: 500mg
Price: $680
Updated: 2021/12/16

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Propargyl-PEG3-Ms Chemical Properties,Usage,Production

Description

Propargyl-PEG3-Ms is a crosslinking reagent with a propargyl group and a mesyl group. The propargyl group reacts with azide-bearing compounds or biomolecules in copper catalyzed Click Chemistry reactions.

Uses

Propargyl-PEG2-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG2-MS is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] Bai S, et al. Synthesis and structure-activity relationship studies of conformationally flexibletetrahydroisoquinolinyl triazole carboxamide and triazole substituted benzamide analogues as σ2 receptor ligands. J Med Chem. 2014 May 22;57(10):4239-51. DOI:10.1021/jm5001453

Propargyl-PEG3-Ms Preparation Products And Raw materials

Raw materials

Preparation Products

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943726-01-0, Propargyl-PEG3-MsRelated Search:

Propargyl-PEG3-methyl ester Propargyl-PEG3-Sulfone-PEG3-Propargyl Propargyl-PEG3-phosphonic acid ethyl ester Propargyl-PEG3-Bromide Propargyl--PEG3-phosphonic acid Propargyl-PEG4-5-nitrophenyl carbonate Propargyl-PEG3-t-butyl ester Propargyl-PEG3-NH2 Propargyl-PEG4-(CH2)3-acid Propargyl-PEG4-(CH2)3-methyl ester

Propargyl-PEG3-Ms

Propargyl-PEG2-Ms

Ethanol, 2-[2-(2-propyn-1-yloxy)ethoxy]-, 1-methanesulfonate

2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate

2-(2-(Prop-2-yn-1-yloxy)ethoxy)ethyl methanesulfonate

2-(2-prop-2-ynoxyethoxy)ethyl methanesulfonate - [P88013]

943726-01-0