Propargyl-PEG3-phosphonic acid ethyl ester
- Product Name
- Propargyl-PEG3-phosphonic acid ethyl ester
- CAS No.
- 1052678-30-4
- Chemical Name
- Propargyl-PEG3-phosphonic acid ethyl ester
- Synonyms
- Propargyl-PEG3-Phosphonic Ester;Propargyl-PEG3-phosphonic acid ethyl ester;Propargyl-PEG3-phosphonic acid diethyl ester;Diethyl [2-[2-[2-(Prop-2-yn-1-yloxy)ethoxy]ethoxy]ethyl]phosphonate;Phosphonic acid, P-[2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]ethyl]-, diethyl ester
- CBNumber
- CB73373760
- Molecular Formula
- C13H25O6P
- Formula Weight
- 308.31
- MOL File
- 1052678-30-4.mol
N-Bromosuccinimide Price
- Product number
- BP-23752
- Product name
- Propargyl-PEG3-phosphonicacidethylester
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23752
- Product name
- Propargyl-PEG3-phosphonicacidethylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-23752
- Product name
- Propargyl-PEG3-phosphonicacidethylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $850
- Updated
- 2021/12/16
Propargyl-PEG3-phosphonic acid ethyl ester Chemical Properties,Usage,Production
Description
Propargyl-PEG3-phosphonic acid ethyl ester is a crosslinker containing a propargyl group and a phosphonic acid ethyl ester. The propargyl group can react with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The hydrophilic PEG spacer increases solubility in aqueous media.
Uses
Propargyl-PEG3-phosphonic acid diethyl ester is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-phosphonic acid diethyl ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] Thorsten Heidelberg, et al. Oligo-ethylene glycol based phosphonate surface modification reagents and use thereof. WO2015065168A1
Propargyl-PEG3-phosphonic acid ethyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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