Propargyl-PEG3-NH2
- Product Name
- Propargyl-PEG3-NH2
- CAS No.
- 932741-19-0
- Chemical Name
- Propargyl-PEG3-NH2
- Synonyms
- NH2-PEG3-Al;Alkyne-PEG3-amine;2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethanamine;3-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)prop-1-yne;2‐(2‐(2‐(prop‐2‐yn‐1‐yloxy)ethoxy)ethoxy)ethanamine;Ethanamine, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-;2-(2-(2-(prop-2-yn-1-yloxy)ethoxy)ethoxy)ethan-1-amine;Propargyl-PEG3-NH2/Ethanamine, 2-[2-[2-(2-propyn-1-yloxy)ethoxy]ethoxy]-
- CBNumber
- CB43975590
- Molecular Formula
- C9H17NO3
- Formula Weight
- 187.24
- MOL File
- 932741-19-0.mol
Propargyl-PEG3-NH2 Property
- Boiling point:
- 267.4±25.0 °C(Predicted)
- Density
- 1.019±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 8.74±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
- Appearance
- colorlessoryellowish liquid
- InChI
- InChI=1S/C9H17NO3/c1-2-4-11-6-8-13-9-7-12-5-3-10/h1H,3-10H2
- InChIKey
- MREICTHRFCQNJR-UHFFFAOYSA-N
- SMILES
- C(N)COCCOCCOCC#C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- AS104189
- Product name
- Propargyl-PEG3-NH2
- Purity
- 95+%
- Packaging
- 1g
- Price
- $361
- Updated
- 2021/12/16
- Product number
- BP-21683
- Product name
- Propargyl-PEG3-amine
- Purity
- 98%
- Packaging
- 1g
- Price
- $550
- Updated
- 2021/12/16
- Product number
- POL0002520
- Product name
- PROPARGYL-PEG3-AMINE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $799.24
- Updated
- 2021/12/16
- Product number
- AS104189
- Product name
- Propargyl-PEG3-NH2
- Purity
- 95+%
- Packaging
- 5G
- Price
- $1040
- Updated
- 2021/12/16
- Product number
- A755212
- Product name
- PRopargyl-PEG3-amine
- Purity
- 97%
- Packaging
- 5g
- Price
- $997
- Updated
- 2021/12/16
Propargyl-PEG3-NH2 Chemical Properties,Usage,Production
Description
Propargyl-PEG3-amine is a PEG linker that is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. The propargyl group reacts with azides in copper catalyzed azide-alkyne Click Chemistry.
Uses
Propargyl-PEG3-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Propargyl-PEG3-amine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Propargyl-PEG3-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
Propargyl-PEG3-NH2 Suppliers
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View Lastest Price from Propargyl-PEG3-NH2 manufacturers
- Product
- Propargyl-PEG3-amine 932741-19-0
- Price
- US $0.00/g
- Min. Order
- 10g
- Purity
- >98.00%
- Supply Ability
- 10g
- Release date
- 2024-03-26