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alpha, oMega-Dipropionic acid hexaethylene glycol

Product Name
alpha, oMega-Dipropionic acid hexaethylene glycol
CAS No.
94376-75-7
Chemical Name
alpha, oMega-Dipropionic acid hexaethylene glycol
Synonyms
Di-Acid-PEG7;Bis-PEG7-COOH;Bis-PEG8-acid;Bis-PEG7-acid;HOOC-PEG6-COOH;COOH-PEG7-COOH;COOH-PEG6-COOH;Bis(3-PEG6)propionic acid;COOHCH2CH2-PEG6-CH2CH2COOH;HOOCCH2CH2O-PEG6-CH2CH2COOH
CBNumber
CB02546887
Molecular Formula
C18H34O11
Formula Weight
426.46
MOL File
94376-75-7.mol
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alpha, oMega-Dipropionic acid hexaethylene glycol Property

form 
Viscous Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

dPEG
Product number
10236
Product name
Bis-dPEG®₇-acid
Packaging
100mg
Price
$200
Updated
2021/12/16
Activate Scientific
Product number
AS104214
Product name
Bis-PEG8-acid
Purity
95+%
Packaging
250mg
Price
$239
Updated
2021/12/16
BroadPharm
Product number
BP-20413
Product name
Bis-PEG7-acid
Purity
98%
Packaging
1g
Price
$400
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
POL0002290
Product name
HOOC-DPEG-(6)-COOH
Purity
95.00%
Packaging
100MG
Price
$400.05
Updated
2021/12/16
chempep
Product number
281803
Product name
HOOC-PEG6-COOH
Purity
>=95%
Packaging
1g
Price
$430
Updated
2021/12/16
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alpha, oMega-Dipropionic acid hexaethylene glycol Chemical Properties,Usage,Production

Description

Bis-PEG7-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bis-PEG7-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG6-propionic acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Biological Activity

Bis-PEG7-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).

target

IC 50

PEGs; Cleavable Linker

References

[1] Marc Stefan ROBILLARD, et al. Tetrazines for high click conjugation yield in vivo and high click release yield. WO2019212356A1

alpha, oMega-Dipropionic acid hexaethylene glycol Preparation Products And Raw materials

Raw materials

Preparation Products

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alpha, oMega-Dipropionic acid hexaethylene glycol Suppliers

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View Lastest Price from alpha, oMega-Dipropionic acid hexaethylene glycol manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Bis-PEG7-acid 94376-75-7
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-23

94376-75-7, alpha, oMega-Dipropionic acid hexaethylene glycolRelated Search:

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  • alpha, oMega-Dipropionic acid hexaethylene glycol
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  • 4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid
  • Bis-PEG7-acid
  • COOH-PEG6-COOH
  • COOH-PEG7-COOH
  • HOOCCH2CH2O-PEG6-CH2CH2COOH
  • Bis-PEG8-acid
  • 3-(2-{2-[2-(2-{2-[2-(2-Carboxyethoxy)ethoxy]ethoxy}ethoxy)ethoxy]ethoxy}-ethoxy)propionic acid
  • Bis-PEG7-COOH
  • Bis(3-PEG6)propionic acid
  • Di-Acid-PEG7
  • HOOCCH2CH2O-PEG6-CH2CH2COOH/4,7,10,13,16,19,22-Heptaoxapentacosanedioic acid
  • 3-[2-[2-[2-[2-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
  • COOHCH2CH2-PEG6-CH2CH2COOH
  • 94376-75-7
  • peg

    • PEGs

    Cleavable