Bis-PEG10-acid
- Product Name
- Bis-PEG10-acid
- CAS No.
- 1268488-70-5
- Chemical Name
- Bis-PEG10-acid
- Synonyms
- Di-Acid-PEG9;Bis-PEG9-COOH;HOOC-PEG8-COOH;COOH-PEG8-COOH;Bis-PEG25-acid;Bis-PEG10-acid;COOHCH2CH2-PEG8-CH2CH2COOH;HOOCCH2CH2-PEG24-CH2CH2COOH;HOOCCH2CH2O-PEG8-CH2CH2COOH;Bis-PEGn-CH2CH2COOH (n=9,25)
- CBNumber
- CB02747165
- Molecular Formula
- C22H42O13
- Formula Weight
- 514.56
- MOL File
- 1268488-70-5.mol
Bis-PEG10-acid Property
- Boiling point:
- 630.0±55.0 °C(Predicted)
- Density
- 1.174±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 3.97±0.10(Predicted)
- form
- Solid
- color
- White to off-white
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B592753
- Product name
- BIS-PEG21-ACID
- Packaging
- 50mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- 0455AP
- Product name
- HOOC-PEG8-COOH
- Packaging
- 1g
- Price
- $1092
- Updated
- 2021/12/16
- Product number
- 10967
- Product name
- Bis-dPEG???-acid
- Packaging
- 1000mg
- Price
- $1300
- Updated
- 2021/12/16
- Product number
- 10320
- Product name
- Bis-dPEG???-acid
- Packaging
- 1000mg
- Price
- $1500
- Updated
- 2021/12/16
- Product number
- 281806
- Product name
- HOOC-PEG8-COOH
- Purity
- >=95%
- Packaging
- 5g
- Price
- $1789
- Updated
- 2021/12/16
Bis-PEG10-acid Chemical Properties,Usage,Production
Description
Bis-PEG9-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bis-??PEG9-??acid is used in the preparation of plasma-stable dimeric inhibitors of PSD-95-NMDA receptor interaction.
Biological Activity
Bis-PEG10-acid is a PROTAC linker belonging to the PEG class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody-drug conjugates (ADCs).
target
| PEGs
| Cleavable
|