Bis-PEG2-acid
- Product Name
- Bis-PEG2-acid
- CAS No.
- 19364-66-0
- Chemical Name
- Bis-PEG2-acid
- Synonyms
- Di-Acid-PEG2;Bis-PEG2-COOH;Bis-PEG2-acid;COOH-PEG1-COOH;HOOCCH2CH2O-PEG1-CH2CH2COOH;1,2-Bis(2-carboxyethoxy)ethane;Ethyleneglycol-bis(propionic acid);3-[2-(2-carboxyethoxy)ethoxy]propanoic acid;3,3'-(ethane-1,2-diylbis(oxy))dipropionic acid;3,3'-[ethane-1,2-diylbis(oxy)]dipropanoic acid
- CBNumber
- CB43062409
- Molecular Formula
- C8H14O6
- Formula Weight
- 206.19
- MOL File
- 19364-66-0.mol
Bis-PEG2-acid Property
- Melting point:
- 66 °C
- Boiling point:
- 407.1±35.0 °C(Predicted)
- Density
- 1.0869 g/cm3(Temp: 4 °C)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in Water, DMF, DMSO
- pka
- 3.97±0.10(Predicted)
- form
- Solid
- color
- White to off-white
- InChI
- 1S/C8H14O6/c9-7(10)1-3-13-5-6-14-4-2-8(11)12/h1-6H2,(H,9,10)(H,11,12)
- InChIKey
- BOXWYBCUJGWEOJ-UHFFFAOYSA-N
- SMILES
- OC(CCOCCOCCC(O)=O)=O
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B593655
- Product name
- Bis-PEG2-Acid
- Packaging
- 100mg
- Price
- $285
- Updated
- 2021/12/16
- Product number
- BP-20588
- Product name
- Bis-PEG2-acid
- Purity
- 98%
- Packaging
- 250mg
- Price
- $340
- Updated
- 2021/12/16
- Product number
- LIN0000138
- Product name
- BIS-PEG2-ACID
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $408
- Updated
- 2021/12/16
- Product number
- 3419CU
- Product name
- Bis-PEG2-acid
- Packaging
- 500mg
- Price
- $455
- Updated
- 2021/12/16
- Product number
- BIPG1247
- Product name
- Bis-PEG2-acid
- Packaging
- 250mg
- Price
- $502
- Updated
- 2021/12/16
Bis-PEG2-acid Chemical Properties,Usage,Production
Description
Bis-PEG2-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.
Uses
Bis-PEG2-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264
Bis-PEG2-acid Preparation Products And Raw materials
Raw materials
Preparation Products
Bis-PEG2-acid Suppliers
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View Lastest Price from Bis-PEG2-acid manufacturers
- Product
- 3,3'-((oxybis(ethane-2,1-diyl))bis(oxy))dipropionic acid 19364-66-0
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 1g/bottle, 10g/bottle, 100g/bottle
- Release date
- 2025-09-10
- Product
- Bis-PEG2-acid 19364-66-0
- Price
- US $0.00/g
- Min. Order
- 5g
- Purity
- >98.00%
- Supply Ability
- 5g
- Release date
- 2024-03-23