α,ω,-dipropionic acid nonaethylene glycol

Product Name: α,ω,-dipropionic acid nonaethylene glycol
CAS No.: 2055023-26-0
Chemical Name: α,ω,-dipropionic acid nonaethylene glycol
Synonyms: Di-Acid-PEG10;Bis-PEG10-COOH;Bis-PEG10-acid bis-;HOOCCH2CH2O-PEG9-CH2CH2COOH;α,ω,-dipropionic acid nonaethylene glycol;4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid;HOOCCH2CH2O-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid
CBNumber: CB03340589
Molecular Formula: C24H46O14
Formula Weight: 558.61
MOL File: 2055023-26-0.mol

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α,ω,-dipropionic acid nonaethylene glycol Property

Boiling point:: 657.7±55.0 °C(Predicted)
Density: 1.169±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, sealed storage, away from moisture
form: Liquid
pka: 3.97±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22504
Product name: Bis-PEG10-acid
Purity: 98%
Packaging: 250mg
Price: $260
Updated: 2021/12/16

BroadPharm

Product number: BP-22504
Product name: Bis-PEG10-acid
Purity: 98%
Packaging: 500mg
Price: $390
Updated: 2021/12/16

BroadPharm

Product number: BP-22504
Product name: Bis-PEG10-acid
Purity: 98%
Packaging: 1g
Price: $510
Updated: 2021/12/16

Activate Scientific

Product number: AS104215
Product name: Bis-PEG10-acid
Purity: 95+%
Packaging: 1g
Price: $618
Updated: 2021/12/16

Acrotein

Product number: B-1186
Product name: HOOCCH2CH2O-PEG9-CH2CH2COOH
Purity: 97%
Packaging: 0.25g
Price: $220
Updated: 2021/12/16

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α,ω,-dipropionic acid nonaethylene glycol Chemical Properties,Usage,Production

Description

Bis-PEG10-acid is a PEG linker containing two terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bis-PEG10-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] Zhao Q, et al. Discovery of SIAIS178 as an Effective BCR-ABL Degrader by Recruiting Von Hippel-Lindau (VHL) E3 Ubiquitin Ligase. J Med Chem. 2019 Oct 24;62(20):9281-9298. DOI:10.1021/acs.jmedchem.9b01264

α,ω,-dipropionic acid nonaethylene glycol Preparation Products And Raw materials

Raw materials

Preparation Products

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α,ω,-dipropionic acid nonaethylene glycol Suppliers

China 34 United States 5 Global 39

T&W GROUP

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View Lastest Price from α,ω,-dipropionic acid nonaethylene glycol manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Bis-PEG10-acid 2055023-26-0
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

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α,ω,-dipropionic acid nonaethylene glycol

HOOCCH2CH2O-PEG9-CH2CH2COOH

Bis-PEG10-COOH

4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid

Di-Acid-PEG10

HOOCCH2CH2O-PEG9-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31-Decaoxatetratriacontanedioic acid

Bis-PEG10-acid bis-

2055023-26-0

C24H46O14