ChemicalBook > CAS DataBase List > HOOC-PEG7-CH2CH2COOH

HOOC-PEG7-CH2CH2COOH

Product Name
HOOC-PEG7-CH2CH2COOH
CAS No.
1246189-43-4
Chemical Name
HOOC-PEG7-CH2CH2COOH
Synonyms
Di-Acid-PEG8;Bis-PEG8-COOH;HOOC-PEG7-COOH;Bis-PEG8-acid BIS-;HOOC-PEG7-CH2CH2COOH;COOHCH2CH2-PEG7-CH2CH2COOH;HOOCCH2CH2O-PEG7-CH2CH2COOH;4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid;4,7,10,13,16,19,22,25-Octaoxaoctacosane-1,28-dioic Acid;HOOCCH2CH2O-PEG7-CH2CH2COOH/4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid
CBNumber
CB73340588
Molecular Formula
C20H38O12
Formula Weight
470.51
MOL File
1246189-43-4.mol
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HOOC-PEG7-CH2CH2COOH Property

Boiling point:
601.8±55.0 °C(Predicted)
Density 
1.179±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.97±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific
Product number
AS104214
Product name
Bis-PEG8-acid
Purity
95+%
Packaging
250mg
Price
$239
Updated
2021/12/16
BroadPharm
Product number
BP-23993
Product name
Bis-PEG8-acid
Purity
98%
Packaging
500mg
Price
$350
Updated
2021/12/16
Activate Scientific
Product number
AS104214
Product name
Bis-PEG8-acid
Purity
95+%
Packaging
1g
Price
$499
Updated
2021/12/16
AK Scientific
Product number
4268EF
Product name
Hoocch2CH2O-peg7-CH2CH2cooh
Packaging
1g
Price
$856
Updated
2021/12/16
Activate Scientific
Product number
AS104214
Product name
Bis-PEG8-acid
Purity
95+%
Packaging
5G
Price
$1402
Updated
2021/12/16
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HOOC-PEG7-CH2CH2COOH Chemical Properties,Usage,Production

Description

Bis-PEG8-acid is a PEG linker containing terminal carboxylic acid groups. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acids can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

Bis-PEG8-acid is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. Bis-PEG8-acid is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

IC 50

PEGs; Cleavable Linker

References

[1] Gregory Slobodkin, et al. Polyamine derivatives. WO2010108108A2

HOOC-PEG7-CH2CH2COOH Preparation Products And Raw materials

Raw materials

Preparation Products

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HOOC-PEG7-CH2CH2COOH Suppliers

T&W GROUP
Tel
021-61551611 13296011611
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9895
Advantage
58
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883
Fax
0731-82251112
Email
sales@huatengsci.com
Country
China
ProdList
5872
Advantage
58
Borenpharm Co., Ltd
Tel
027-65563561
Fax
86-27-59218822
Email
sales@borenpharm.com
Country
China
ProdList
1245
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55
Shanghai Haozhixiang Biotechnology Co., Ltd
Tel
526763801 13301653310
Fax
+86-21-51619052
Email
526763801@qq.com
Country
China
ProdList
9274
Advantage
55
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
71826
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 18892239720
Fax
010-60605840
Email
psaitong@jm-bio.com
Country
China
ProdList
12306
Advantage
58
Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28785
Advantage
58
Hangzhou HanLai Biochemical Technology Co., Ltd.
Tel
571-86101219 18768477782
Fax
-
Email
sales09@leobiochem.com
Country
China
ProdList
433
Advantage
58
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
Advantage
58
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View Lastest Price from HOOC-PEG7-CH2CH2COOH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Bis-PEG8-acid 1246189-43-4
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-23

1246189-43-4, HOOC-PEG7-CH2CH2COOHRelated Search:


  • HOOC-PEG7-CH2CH2COOH
  • HOOCCH2CH2O-PEG7-CH2CH2COOH
  • 4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid
  • Bis-PEG8-COOH
  • 4,7,10,13,16,19,22,25-Octaoxaoctacosane-1,28-dioic Acid
  • Di-Acid-PEG8
  • HOOCCH2CH2O-PEG7-CH2CH2COOH/4,7,10,13,16,19,22,25-Octaoxaoctacosanedioic acid
  • Bis-PEG8-acid BIS-
  • COOHCH2CH2-PEG7-CH2CH2COOH
  • HOOC-PEG7-COOH
  • 1246189-43-4
  • C20H38O12
  • peg