Acid-PEG5-mono-methyl ester
- Product Name
- Acid-PEG5-mono-methyl ester
- CAS No.
- 1309460-30-7
- Chemical Name
- Acid-PEG5-mono-methyl ester
- Synonyms
- COOH-PEG5-COOMe;COOH-PEG5-CH2CH2COOMe;Acid-PEG5-Methyl Ester;Acid-PEG5-mono-methyl ester;MeOOCCH2CH2O-PEG4-CH2CH2COOH;3-oxo-2,6,9,12,15,18-hexaoxahenicosan-21-oic acid;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-methyl ester
- CBNumber
- CB73062293
- Molecular Formula
- C15H28O9
- Formula Weight
- 352.38
- MOL File
- 1309460-30-7.mol
Acid-PEG5-mono-methyl ester Property
- Boiling point:
- 469.4±45.0 °C(Predicted)
- Density
- 1.151±0.06 g/cm3(Predicted)
- solubility
- Soluble in DCM
- pka
- 4.28±0.10(Predicted)
- form
- Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- C183735
- Product name
- Carboxyl-PEG5-mono-methylEster
- Packaging
- 5mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- BP-20440
- Product name
- Acid-PEG5-mono-methylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
- Product number
- BP-20440
- Product name
- Acid-PEG5-mono-methylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $850
- Updated
- 2021/12/16
Acid-PEG5-mono-methyl ester Chemical Properties,Usage,Production
Description
Acid-PEG5-mono-methyl ester is a PEG linker containing a terminal carboxylic acid and a mono-methyl ester functional group. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of compounds in aqueous media.
Uses
Acid-PEG5-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG5-mono-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Acid-PEG5-mono-methyl ester Suppliers
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View Lastest Price from Acid-PEG5-mono-methyl ester manufacturers
- Product
- COOH-PEG5-COOMe 1309460-30-7
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- >98.00%
- Supply Ability
- 1g
- Release date
- 2024-03-23