ChemicalBook > CAS DataBase List > Acid-PEG6-mono-methyl ester
Acid-PEG6-mono-methyl ester
- Product Name
- Acid-PEG6-mono-methyl ester
- CAS No.
- 1807512-38-4
- Chemical Name
- Acid-PEG6-mono-methyl ester
- Synonyms
- COOH-PEG6-COOMe;COOH-PEG6-CH2CH2COOMe;Acid-PEG6-Methyl Ester;Acid-PEG6-mono-methyl ester;MeOOCCH2CH2O-PEG5-CH2CH2COOH;3-Oxo-2,6,9,12,15,18,21-heptaoxatetracosan-24-oic acid;4,7,10,13,16,19-Hexaoxadocosanedioic acid, 1-methyl ester;3-[2-[2-[2-[2-[2-(3-methoxy-3-oxopropoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
- CBNumber
- CB63062296
- Molecular Formula
- C17H32O10
- Formula Weight
- 396.43
- MOL File
- 1807512-38-4.mol
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Acid-PEG6-mono-methyl ester Property
- Boiling point:
- 503.7±50.0 °C(Predicted)
- Density
- 1.147±0.06 g/cm3(Predicted)
- solubility
- Soluble in Water, DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22815
- Product name
- Acid-PEG6-mono-methylester
- Purity
- 98%
- Packaging
- 250mg
- Price
- $540
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22815
- Product name
- Acid-PEG6-mono-methylester
- Purity
- 98%
- Packaging
- 500mg
- Price
- $850
- Updated
- 2021/12/16
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Acid-PEG6-mono-methyl ester Chemical Properties,Usage,Production
Description
Acid-PEG6-mono-methyl ester is a PEG linker containing a terminal carboxylic acid and a methyl ester group. The carboxylic acid can react with primary amine groups in the presence of activators such as EDC and HATU to form stable amide bonds. The hydrophilic PEG linkers increase the water solubility of a compound in aqueous media. The water solubility properties of the PEG chain are enhanced with longer PEG chains.
Uses
Acid-PEG6-mono-methyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG6-mono-methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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Acid-PEG6-mono-methyl ester Suppliers
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- China
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View Lastest Price from Acid-PEG6-mono-methyl ester manufacturers
Xian confluore Biological Technology Co., Ltd.
- Product
- COOH-PEG6-COOMe 1807512-38-4
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-23
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