Acid-PEG3-NHS ester

Product Name: Acid-PEG3-NHS ester
CAS No.: 1835759-79-9
Chemical Name: Acid-PEG3-NHS ester
Synonyms: COOH-PEG3-SPA;COOH-PEG3-NHS;Acid-PEG3-NHS ester;Acid-C2-PEG3-NHS ester;3-(2-(2-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropoxy)ethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]-, 1-(2,5-dioxo-1-pyrrolidinyl) ester
CBNumber: CB13162821
Molecular Formula: C14H21NO9
Formula Weight: 347.32
MOL File: 1835759-79-9.mol

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Acid-PEG3-NHS ester Property

Boiling point:: 516.1±60.0 °C(Predicted)
Density: 1.34±0.1 g/cm3(Predicted)
solubility: Soluble in DMSO, DCM, DMF
pka: 4.28±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-22972
Product name: Acid-PEG3-NHSester
Purity: 95%
Packaging: 250mg
Price: $580
Updated: 2021/12/16

BroadPharm

Product number: BP-22972
Product name: Acid-PEG3-NHSester
Purity: 95%
Packaging: 1g
Price: $1450
Updated: 2021/12/16

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Acid-PEG3-NHS ester Chemical Properties,Usage,Production

Description

Acid-PEG3-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.

Uses

Acid-C2-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG3-NHS ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Acid-PEG3-NHS ester Suppliers

China 25 United States 3 Global 28

Jinan elephant international trading co., LTD

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Xi'an Confluore Biological Technology Co., Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
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Nextpeptide Inc

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Chongqing Chemdad Co., Ltd

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Changsha Bono New Materials Technology Co., Ltd.

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Shanghai Sunway Pharmaceutical Technology Co.,Ltd.

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Zhengzhou Akem Chemical Co., Ltd

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Beijing Jin Ming Biotechnology Co., Ltd.

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View Lastest Price from Acid-PEG3-NHS ester manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: Acid-PEG3-NHS ester 1835759-79-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

Xian confluore Biological Technology Co., Ltd.

Product: Acid-PEG3-NHS ester 1835759-79-9
Price: US $0.00/mg
Min. Order: 500mg
Purity: >98.00%
Supply Ability: 500mg
Release date: 2024-03-23

1835759-79-9, Acid-PEG3-NHS esterRelated Search:

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Acid-PEG3-NHS ester

COOH-PEG3-NHS

Acid-C2-PEG3-NHS ester

Propanoic acid, 3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]-, 1-(2,5-dioxo-1-pyrrolidinyl) ester

COOH-PEG3-SPA

3-(2-(2-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropoxy)ethoxy)ethoxy)propanoic acid

1835759-79-9

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