ChemicalBook > CAS DataBase List > Acid-PEG3-NHS ester
Acid-PEG3-NHS ester
- Product Name
- Acid-PEG3-NHS ester
- CAS No.
- 1835759-79-9
- Chemical Name
- Acid-PEG3-NHS ester
- Synonyms
- COOH-PEG3-SPA;COOH-PEG3-NHS;Acid-PEG3-NHS ester;Acid-C2-PEG3-NHS ester;3-(2-(2-(3-((2,5-dioxopyrrolidin-1-yl)oxy)-3-oxopropoxy)ethoxy)ethoxy)propanoic acid;Propanoic acid, 3-[2-[2-(2-carboxyethoxy)ethoxy]ethoxy]-, 1-(2,5-dioxo-1-pyrrolidinyl) ester
- CBNumber
- CB13162821
- Molecular Formula
- C14H21NO9
- Formula Weight
- 347.32
- MOL File
- 1835759-79-9.mol
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Acid-PEG3-NHS ester Property
- Boiling point:
- 516.1±60.0 °C(Predicted)
- Density
- 1.34±0.1 g/cm3(Predicted)
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 4.28±0.10(Predicted)
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N-Bromosuccinimide Price
BroadPharm
- Product number
- BP-22972
- Product name
- Acid-PEG3-NHSester
- Purity
- 95%
- Packaging
- 250mg
- Price
- $580
- Updated
- 2021/12/16
BroadPharm
- Product number
- BP-22972
- Product name
- Acid-PEG3-NHSester
- Purity
- 95%
- Packaging
- 1g
- Price
- $1450
- Updated
- 2021/12/16
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Acid-PEG3-NHS ester Chemical Properties,Usage,Production
Description
Acid-PEG3-NHS ester is a PEG linker containing a carboxylic acid and an NHS ester. The hydrophilic PEG spacer increases solubility in aqueous media. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
Uses
Acid-C2-PEG3-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Acid-PEG3-NHS ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Acid-PEG3-NHS ester manufacturers
Henan Aochuang Chemical Co.,Ltd.
- Product
- Acid-PEG3-NHS ester 1835759-79-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-27
Xian confluore Biological Technology Co., Ltd.
- Product
- Acid-PEG3-NHS ester 1835759-79-9
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >98.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-23
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