Acid-PEG3-mono-methyl ester

Product Name: Acid-PEG3-mono-methyl ester
CAS No.: 1807505-26-5
Chemical Name: Acid-PEG3-mono-methyl ester
Synonyms: COOH-PEG3-COOMe;CAS_1807505-26-5;COOH-PEG3-CH2CH2COOMe;Acid-PEG3-mono-methyl ester;MeOOCCH2CH2O-PEG2-CH2CH2COOH;CARBOXY-PEG3-MONO-METHYL ESTER;4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-;3-Oxo-2,6,9,12-tetraoxapentadecan-15-oic Acid;MeOOCCH2CH2O-PEG2-CH2CH2COOH/4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-
CBNumber: CB13062291
Molecular Formula: C11H20O7
Formula Weight: 264.27
MOL File: 1807505-26-5.mol

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Acid-PEG3-mono-methyl ester Property

Boiling point:: 396.7±32.0 °C(Predicted)
Density: 1.162±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
form: Liquid
pka: 4.27±0.10(Predicted)
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Activate Scientific

Product number: AS108037
Product name: Carboxy-PEG3-mono-Methylester
Purity: 94%
Packaging: 250mg
Price: $531
Updated: 2021/12/16

BroadPharm

Product number: BP-22142
Product name: Acid-PEG3-mono-methylester
Purity: 92%
Packaging: 250mg
Price: $540
Updated: 2021/12/16

Apolloscientific

Product number: BIPG1358
Product name: Carboxy-PEG3-mono-methyl ester
Packaging: 250mg
Price: $623
Updated: 2021/12/16

BroadPharm

Product number: BP-22142
Product name: Acid-PEG3-mono-methylester
Purity: 92%
Packaging: 500mg
Price: $850
Updated: 2021/12/16

BroadPharm

Product number: BP-22142
Product name: Acid-PEG3-mono-methylester
Purity: 92%
Packaging: 1g
Price: $1250
Updated: 2021/12/16

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Acid-PEG3-mono-methyl ester Chemical Properties,Usage,Production

Description

Acid-PEG3-mono-methyl ester is a PEG linker with a carboxylic acid and methyl ester group. Methyl ester can be hydrolyzed under strong basic condition. The carboxylic acid can react with primary amines in the presence of EDC and HATU to form stable amide bonds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous media.

Uses

Acid-PEG3-mono-methyl ester is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG3-mono-methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Acid-PEG3-mono-methyl ester Suppliers

China 42 United Kingdom 1 United States 4 Global 47

Borenpharm Co., Ltd

Tel: 027-65563561
Fax: 86-27-59218822
Email: sales@borenpharm.com
Country: China
ProdList: 1245
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Jinan elephant international trading co., LTD

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Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-0371-55629727 13323845623
Fax: 037155629727
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Country: China
ProdList: 10043
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Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28774
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Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
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Country: China
ProdList: 4952
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Henan Alfachem Co.,Ltd.

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Alpha Biopharmaceuticals Co., Ltd

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TargetMol Chemicals Inc.

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Email: marketing@targetmol.com
Country: United States
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Nextpeptide Inc

Tel: +86-0571-81612335 +8613336028439
Email: sales@nextpeptide.com
Country: China
ProdList: 19908
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View Lastest Price from Acid-PEG3-mono-methyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: COOH-PEG3-COOMe 1807505-26-5
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1807505-26-5, Acid-PEG3-mono-methyl esterRelated Search:

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Acid-PEG3-mono-methyl ester

CARBOXY-PEG3-MONO-METHYL ESTER

CAS_1807505-26-5

COOH-PEG3-COOMe

4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-

MeOOCCH2CH2O-PEG2-CH2CH2COOH

MeOOCCH2CH2O-PEG2-CH2CH2COOH/4,7,10,14-Tetraoxapentadecanoic acid, 13-oxo-

3-Oxo-2,6,9,12-tetraoxapentadecan-15-oic Acid

COOH-PEG3-CH2CH2COOMe

1807505-26-5