Acid-PEG5-t-butyl ester

Product Name: Acid-PEG5-t-butyl ester
CAS No.: 1309460-29-4
Chemical Name: Acid-PEG5-t-butyl ester
Synonyms: COOH-PEG5-OtBu;Acid-PEG5-C2-Boc;COOH-PEG5-COOtBu;Acid-PEG5-t-Bu Ester;Acid-PEG5-t-butyl ester;Carboxy-PEG5-tert-butyl Ester;HOOCCH2CH2O-PEG4-CH2CH2COOtBu;2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid;4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester;2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid , Acid-PEG5-C2-Boc
CBNumber: CB33062295
Molecular Formula: C18H34O9
Formula Weight: 394.46
MOL File: 1309460-29-4.mol

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Acid-PEG5-t-butyl ester Property

Boiling point:: 495.2±45.0 °C(Predicted)
Density: 1.109±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 4.28±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C18H34O9/c1-18(2,3)27-17(21)5-7-23-9-11-25-13-15-26-14-12-24-10-8-22-6-4-16(19)20/h4-15H2,1-3H3,(H,19,20)
InChIKey: ILIIUHKWCBCCNI-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCOCCC(O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: C183738
Product name: Carboxy-PEG5-t-butylEster
Packaging: 1mg
Price: $45
Updated: 2021/12/16

BroadPharm

Product number: BP-20439
Product name: Acid-PEG5-t-butylester
Purity: 95%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

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Acid-PEG5-t-butyl ester Chemical Properties,Usage,Production

Description

Acid-PEG5-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Acid-PEG5-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Acid-PEG5-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Acid-PEG5-t-butyl ester Suppliers

China 47 United States 4 Global 51

CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD

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View Lastest Price from Acid-PEG5-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: COOH-PEG5-COOtBu 1309460-29-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1309460-29-4, Acid-PEG5-t-butyl esterRelated Search:

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Acid-PEG5-t-butyl ester

COOH-PEG5-OtBu

COOH-PEG5-COOtBu

Acid-PEG5-C2-Boc

4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester

HOOCCH2CH2O-PEG4-CH2CH2COOtBu

Acid-PEG5-t-Bu Ester

HOOCCH2CH2O-PEG4-CH2CH2COOtBu/4,7,10,13,16-Pentaoxanonadecanedioic acid, 1-(1,1-dimethylethyl) ester

2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid

2,2-Dimethyl-4-oxo-3,7,10,13,16,19-hexaoxadocosan-22-oic acid , Acid-PEG5-C2-Boc

Carboxy-PEG5-tert-butyl Ester

1309460-29-4

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