HOOCCH2CH2-PEG16-CH2CH2COOH
- Product Name
- HOOCCH2CH2-PEG16-CH2CH2COOH
- CAS No.
- 2226897-74-9
- Chemical Name
- HOOCCH2CH2-PEG16-CH2CH2COOH
- Synonyms
- Di-Acid-PEG17;COOH-PEG17-CH2CH2COOH;HOOCCH2CH2-PEG16-CH2CH2COOH;4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid;HOOCCH2CH2O-PEG16-CH2CH2COOH/4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52-Heptadecaoxapentapentacontanedioic acid
- CBNumber
- CB84868345
- Molecular Formula
- C38H74O21
- Formula Weight
- 866.98
- MOL File
- 2226897-74-9.mol
HOOCCH2CH2-PEG16-CH2CH2COOH Property
- storage temp.
- 2-8°C, sealed storage, away from moisture
- form
- Solid
- color
- Off-white to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 233216
- Product name
- HOOC-PEG16-COOH
- Purity
- min.97%
- Packaging
- 250mg
- Price
- $300
- Updated
- 2021/12/16
HOOCCH2CH2-PEG16-CH2CH2COOH Chemical Properties,Usage,Production
Uses
Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Biological Activity
Bis-PEG17-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
IC 50
PEGs
References
[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
HOOCCH2CH2-PEG16-CH2CH2COOH Preparation Products And Raw materials
Raw materials
Preparation Products
HOOCCH2CH2-PEG16-CH2CH2COOH Suppliers
- Tel
- 0512-56316828
- Fax
- 0512-56316826
- info@amateksci.com
- Country
- China
- ProdList
- 28772
- Advantage
- 58
- Tel
- +86-156-80926068 +86-15680926068
- 1924344760@qq.com
- Country
- China
- ProdList
- 4952
- Advantage
- 58
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32467
- Advantage
- 58
- Tel
- 18201884268
- magean83@163.com
- Country
- China
- ProdList
- 2364
- Advantage
- 58
- Tel
- 15817493340
- 981810490@qq.com
- Country
- China
- ProdList
- 1566
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58
- Tel
- 400-1647117 13681763483
- product02@bidepharm.com
- Country
- China
- ProdList
- 59936
- Advantage
- 58
- Tel
- 15841022315
- sales@affinitytech.cn
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 0431-80514535 19917294565
- et@chemextension.com
- Country
- China
- ProdList
- 5061
- Advantage
- 58
- Tel
- 021-50795510 4000665055
- marketing@accelachem.com
- Country
- China
- ProdList
- 9746
- Advantage
- 58
View Lastest Price from HOOCCH2CH2-PEG16-CH2CH2COOH manufacturers
- Product
- Bis-PEG17-acid 2226897-74-9
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >98.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-27