Acid-PEG4-t-butyl ester

Product Name: Acid-PEG4-t-butyl ester
CAS No.: 1835759-85-7
Chemical Name: Acid-PEG4-t-butyl ester
Synonyms: COOH-PEG4-OtBu;Acid-PEG4-C2-Boc;COOH-PEG4-COOtBu;Acid-PEG4-t-Bu Ester;Acid-PEG4-t-butyl ester;Acid-PEG4-tert-butyl Ester;HOOCCH2CH2O-PEG3-CH2CH2COOtBu;Di-tert-butyl 4,7,10,13-tetraoxahexadecane-1,16-dioate;2,2-Dimethyl-4-oxo-3,7,10,13,16-pentaoxanonadecan-19-oic acid;4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester
CBNumber: CB63162826
Molecular Formula: C20H38O8
Formula Weight: 350.4
MOL File: 1835759-85-7.mol

More

Less

Acid-PEG4-t-butyl ester Property

Boiling point:: 460.1±40.0 °C(Predicted)
Density: 1.107±0.06 g/cm3(Predicted)
storage temp.: Storage temp. 2-8°C
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 4.28±0.10(Predicted)
form: Liquid
color: Colorless to light yellow
InChI: InChI=1S/C16H30O8/c1-16(2,3)24-15(19)5-7-21-9-11-23-13-12-22-10-8-20-6-4-14(17)18/h4-13H2,1-3H3,(H,17,18)
InChIKey: LXMHKDZTUDTSCT-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCOCCOCCOCCOCCC(O)=O

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

BroadPharm

Product number: BP-22933
Product name: Acid-PEG4-t-butylester
Purity: 95%
Packaging: 100mg
Price: $380
Updated: 2021/12/16

BroadPharm

Product number: BP-22933
Product name: Acid-PEG4-t-butylester
Purity: 95%
Packaging: 500mg
Price: $980
Updated: 2021/12/16

Absolute Chiral

Product number: A2133-00-N
Product name: di-tert-butyl4,7,10,13-tetraoxahexadecane-1,16-dioate
Purity: 95%
Packaging: 100mg
Price: $298
Updated: 2021/12/16

More

Less

Acid-PEG4-t-butyl ester Chemical Properties,Usage,Production

Description

Acid-PEG4-t-butyl ester is a PEG linker containing a t-butyl protected carboxyl group with a terminal carboxylic acid. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions.

Uses

Acid-PEG4-C2-Boc is a PEG- and Alkyl/ether-based PROTAC linker can be used in the synthesis of PROTACs for the inhibition of mTOR[1].

IC 50

PEGs; Alkyl/ether

References

[1] Jennifer PITZEN , et al. C40-, c28-, and c-32-linked rapamycin analogs as mtor inhibitors. WO2019212990A1.

Acid-PEG4-t-butyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

Acid-PEG4-t-butyl ester Suppliers

China 52 United States 5 Global 57

Jilin Shengchuang Biotechnology Co., LTD

Tel: 19975838191
Email: 396921152@qq.com
Country: China
ProdList: 166
Advantage: 58

CHENGDU YINGNUOLING PHARMACEUTICAL TECHNOLOGY CO.,LTD

Tel: 17882285575
Email: 1276966012@qq.com
Country: China
ProdList: 390
Advantage: 58

Nanjing Junnahe Biopharmaceutical Co., Ltd

Tel: 025-58367986 17351780683
Fax: QQ3209878052
Email: amy.xiang@ally-chem.com
Country: China
ProdList: 354
Advantage: 60

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883
Fax: 0731-82251112
Email: sales@huatengsci.com
Country: China
ProdList: 5872
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

Amatek Scientific Co. Ltd.

Tel: 0512-56316828
Fax: 0512-56316826
Email: info@amateksci.com
Country: China
ProdList: 28785
Advantage: 58

Hangzhou HanLai Biochemical Technology Co., Ltd.

Tel: 571-86101219 18768477782
Fax: -
Email: sales09@leobiochem.com
Country: China
ProdList: 433
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9713
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 400821072
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 25000
Advantage: 58

More

Less

View Lastest Price from Acid-PEG4-t-butyl ester manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: COOH-PEG4-COOtBu 1835759-85-7
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1835759-85-7, Acid-PEG4-t-butyl esterRelated Search:

Hydroxy-PEG5-acid Ald--Ph-PEG2-NHS Ald-PEG4-NHS ester Ald-Ph-PEG6-t-butyl ester Ald-Ph-PEG3-Azide m-PEG4-CH2-aldehyde Ald-PEG5-Azide HOOCCH2CH2O-PEG10-CH2CH2COOH HOOCCH2CH2-PEG16-CH2CH2COOH HO-PEG5-CH2COOtBu Acid-PEG5-t-butyl ester Acid-PEG3-mono-methyl ester Acid-PEG5-NHS ester Acid-PEG25-NHS ester Acid-PEG5-mono-methyl ester Acid-PEG6-mono-methyl ester Acid-PEG3-t-butyl ester Acid-PEG9-NHS ester

Acid-PEG4-t-butyl ester

Di-tert-butyl 4,7,10,13-tetraoxahexadecane-1,16-dioate

COOH-PEG4-COOtBu

Acid-PEG4-C2-Boc

4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester

COOH-PEG4-OtBu

2,2-Dimethyl-4-oxo-3,7,10,13,16-pentaoxanonadecan-19-oic acid

HOOCCH2CH2O-PEG3-CH2CH2COOtBu

Acid-PEG4-t-Bu Ester

HOOCCH2CH2O-PEG3-CH2CH2COOtBu/4,7,10,13-Tetraoxahexadecanedioic acid, 1-(1,1-dimethylethyl) ester

Acid-PEG4-tert-butyl Ester

3-[2-[2-[2-(3-tert-butoxy-3-oxo-propoxy)ethoxy]ethoxy]ethoxy]propanoic acid

3-[2-[2-[2-[3-[(2-methylpropan-2-yl)oxy]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]propanoic acid

1835759-85-7

peg