Ald-Ph-PEG3-Azide
- Product Name
- Ald-Ph-PEG3-Azide
- CAS No.
- 1807540-88-0
- Chemical Name
- Ald-Ph-PEG3-Azide
- Synonyms
- DF-PEG3-N3;ALD-PH-PEG3-N3;Ald-Ph-PEG3-Azide;CHO-Ph-PEG3-azide;CHO-Ph-CONH-PEG3-azide;Ald-Ph-amido-C2-PEG3-azide
- CBNumber
- CB13062307
- Molecular Formula
- C16H22N4O5
- Formula Weight
- 350.38
- MOL File
- 1807540-88-0.mol
Ald-Ph-PEG3-Azide Property
- solubility
- Soluble in DMSO, DCM, DMF
- form
- Oil
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-22380
- Product name
- Ald-Ph-PEG3-azide
- Purity
- 95%
- Packaging
- 100mg
- Price
- $280
- Updated
- 2021/12/16
- Product number
- BP-22380
- Product name
- Ald-Ph-PEG3-azide
- Purity
- 95%
- Packaging
- 250mg
- Price
- $460
- Updated
- 2021/12/16
- Product number
- BP-22380
- Product name
- Ald-Ph-PEG3-azide
- Purity
- 95%
- Packaging
- 500mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- BP-22380
- Product name
- Ald-Ph-PEG3-azide
- Purity
- 95%
- Packaging
- 1g
- Price
- $990
- Updated
- 2021/12/16
Ald-Ph-PEG3-Azide Chemical Properties,Usage,Production
Description
Ald-Ph-PEG3-azide is a PEG reagent containing a benzaldehyde group and a terminal azide group. The benzaldehyde can react with primary amines. The azide can react with alkynes, DBCO and BCN moieties via Click Chemistry reactions.
Uses
Ald-Ph-amido-C2-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Ald-Ph-amido-C2-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005
Ald-Ph-PEG3-Azide Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ald-Ph-PEG3-Azide manufacturers
- Product
- CHO-Ph-CONH-PEG3-azide 1807540-88-0
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >95.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-23