Ald-Ph-PEG4-t-butyl ester
- Product Name
- Ald-Ph-PEG4-t-butyl ester
- CAS No.
- 1807518-64-4
- Chemical Name
- Ald-Ph-PEG4-t-butyl ester
- Synonyms
- Ald-Ph-PEG4-Boc;Ald-Ph-PEG4-COOtBu;CHO-Ph-PEG4-COOtBu;DF-PEG4-CH2CH2COOtBu;CHO-Ph-CONH-PEG4-COOtBu;ALD-PH-PEG4-CH2CH2COOTBU;Ald-Ph-PEG4-t-butyl ester;Ald-Ph-PEG4-t-butyl ester Ald-Ph-;tert-butyl 1-(4-formylphenyl)-1-oxo-5,8,11,14-tetraoxa-2-azaheptadecan-17-oate;4,7,10,13-Tetraoxa-16-azaheptadecanoic acid, 17-(4-formylphenyl)-17-oxo-, 1,1-dimethylethyl ester
- CBNumber
- CB73062309
- Molecular Formula
- C23H35NO8
- Formula Weight
- 453.53
- MOL File
- 1807518-64-4.mol
Ald-Ph-PEG4-t-butyl ester Property
- Boiling point:
- 606.4±55.0 °C(Predicted)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 13.53±0.46(Predicted)
- form
- Viscous Liquid
- color
- Colorless to light yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- BP-22771
- Product name
- Ald-Ph-PEG4-t-butylester
- Purity
- 95%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-22771
- Product name
- Ald-Ph-PEG4-t-butylester
- Purity
- 95%
- Packaging
- 250mg
- Price
- $480
- Updated
- 2021/12/16
- Product number
- BIPG1025
- Product name
- Ald-Ph-PEG4-t-butylester
- Packaging
- 100mg
- Price
- $544
- Updated
- 2021/12/16
- Product number
- BP-22771
- Product name
- Ald-Ph-PEG4-t-butylester
- Purity
- 95%
- Packaging
- 500mg
- Price
- $750
- Updated
- 2021/12/16
Ald-Ph-PEG4-t-butyl ester Chemical Properties,Usage,Production
Description
Ald-Ph-PEG4-t-butyl ester contains a benzaldehyde group which can react with aminooxy (ONH2) bearing molecules. The t-butyl ester is a protecting group that can be removed under acidic conditions for further conjugation, PEG space improve aqueous solubility.
Uses
Ald-Ph-PEG4-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Ald-Ph-PEG4-t-butyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ald-Ph-PEG4-t-butyl ester manufacturers
- Product
- CHO-Ph-CONH-PEG4-COOtBu 1807518-64-4
- Price
- US $0.00/mg
- Min. Order
- 500mg
- Purity
- >97.00%
- Supply Ability
- 500mg
- Release date
- 2024-03-23